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TranscriptomicsHigh Resolution Copy Number Analysis of Paraffin Embedded Archival Tissue Using SNP BeadArrays
High density SNP microarrays provide insight into the genomic events that occur in diseases like cancer by their capability to measure both LOH and genomic copy numbers. Where currently available methods are restricted to the use of fresh frozen tissue, we now describe the design and validation of c...
ORGANISM(S): Homo sapiens 
2006-09-01 | E-GEOD-5347 | biostudies-arrayexpress
UnknownGenomic analysis reveals recurrent deletion of JAK-STAT signaling inhibitors HNRNPK and SOCS1 in mycosis fungoides.
Not available
S-EPMC6282857 | biostudies-literature
TranscriptomicsChordoma_32k_1Mb
Frequent deletion of the CDKN2A locus in chordoma: analysis of chromosomal imbalances using array comparative genomic hybridization DNA copy number analysis of 21 fresh frozen chordoma biopsies, and the respective relapse in four of them, using 32k and 1Mb array CGH. All cases showed copy number al...
ORGANISM(S): Homo sapiens 
2008-01-24 | E-GEOD-9023 | biostudies-arrayexpress
TranscriptomicsGenomic alterations and gene expression in primary diffuse large B cell lymphomas of immune privileged sites
Primary diffuse large B cell lymphomas of different immune-privileged sites (IP-DLBCL) share many clinical and biological features, such as a relatively poor prognosis, preferential dissemination to other immune-privileged sites and deletion of the HLA region, which suggests that IP-DLBCL represents...
ORGANISM(S): Homo sapiens 
2008-06-18 | E-GEOD-10524 | biostudies-arrayexpress
TranscriptomicsaCGH analysis of Palb2GT/+;p53-/- and Palb2+/+;p53-/- lymphomas
Palb2 interacts with BRCA1 and BRCA2 in supercomplexes involved in DNA repair via homologous recombination. Heterozygous germline mutations in PALB2 confer a moderate risk of breast cancer while biallelic PALB2 mutations are linked to a severe form of Fanconi anaemia characterized by early childhood...
ORGANISM(S): Mus musculus 
2011-01-21 | E-GEOD-26723 | biostudies-arrayexpress
UnknownMachine learning analysis of gene expression data reveals novel diagnostic and prognostic biomarkers and identifies therapeutic targets for soft tissue sarcomas.
Not available
S-EPMC6398862 | biostudies-literature
UnknownEvaluation of high-resolution microarray platforms for genomic profiling of bone tumours.
Not available
S-EPMC2929238 | biostudies-literature
TranscriptomicsGenome-wide gene expression profiling of mesenchymal stem cells
Genome-wide gene expression profiling of mesenchymal stem cells (MSCs). 12 MSC samples were hybridized on Illumina Human-6 v2.0 BeadChips.
ORGANISM(S): Homo sapiens 
2012-03-27 | E-GEOD-28974 | biostudies-arrayexpress
TranscriptomicsGenome-wide gene expression profiling of mesenchymal stem cells, osteosarcoma cells, and osteosarcoma cell lines.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-12-19 | E-GEOD-42352 | biostudies-arrayexpress
UnknownSequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic Landscapes.
Not available
S-EPMC4519945 | biostudies-literature
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