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T4 Phage Genome Content in Escherichia coli with PD-T4-3 (PRJCA042586)
After the attachment of the lytic phage T4 to Escherichia coli cells, 1% E. coli cells showed an approximately 40-fold increase in mutant frequency. They were designated as mutator A global transcriptome analysis using microarrays was conducted to determine the difference between parental strain and...
ORGANISM(S): Escherichia coli K-12 
T4 Phage Genome Content in Escherichia coli (PRJCA042587)
T4 genome/PD-T4-3 (PRJCA042585)
Bacteriophages are highly abundant viruses of bacteria. The major role of phages in microbial ecology to shape bacterial communities and their emerging medical potential as antibacterial agents have triggered a rebirth of phage research. It is of particular interest to understand the molecular mecha...
ORGANISM(S): Escherichia coli 
2022-09-19 | PXD035873 | Pride
We investigated the effect of the T4 MotB protein on E. coli gene expression. E. coli BL21 (DE3) containing either pNW129 or pNW129-MotB were grown to early log phase (OD600 ~ 0.3) then induced with 0.2% arabinose for 20 minutes. T4 phage added to the culture at MOI10. Cells were then harvested at ...
ORGANISM(S): Escherichia coli 
2022-10-13 | PXD036347 | Pride
The bacteriophage T4 MotB protein, a DNA-binding protein, improves phage fitness
Rapidly growing antibiotic resistance among gastrointestinal pathogens, and the ability of antibiotics to induce the virulence of these pathogens makes it increasingly difficult to rely on antibiotics to treat gastrointestinal infections. The probiotic E. coli strain Nissle 1917 (EcN) is the active ...
ORGANISM(S): Escherichia coli 
2019-08-27 | GSE135946 | GEO
RNA sequencing of E. coli and B. subtilis infected with phage T4 and phage SPO1, respectively.
Bacteriophage lambda is one of the most extensively studied organisms, and has been a primary model for understanding basic modes of genetic regulation. Here we examine the progress of lambda gene expression during phage development by ribosome profiling, and thereby provide a very high resolution ...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
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