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ProteomicsProteolytic-independent role of mycosins in stabilization of the ESX-1 and ESX-5 type VII secretion membrane complexes.
Pathogenic mycobacteria contain up to five type VII secretion (T7S) systems, ESX-1 to ESX-5, which have central roles in virulence and viability. One of the conserved components of these systems, the serine protease mycosin (MycP), has been shown to be essential for secretion by ESX-1 and ESX-5. How...
ORGANISM(S): Mycobacterium marinum ATCC BAA-535 
2016-10-11 | PXD003766 | Pride
Mycobacterium marinum Tuberculosis Esx1 Single-shot Esx5 Label-free T7s 
UnknownMycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes.
Not available
S-EPMC5082899 | biostudies-literature
UnknownSubstrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Not available
S-EPMC4409929 | biostudies-literature
UnknownIdentification of a substrate domain that determines system specificity in mycobacterial type VII secretion systems.
Not available
S-EPMC5311947 | biostudies-literature
UnknownRD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection.
Not available
S-EPMC6023246 | biostudies-literature
UnknownThe ESX/type VII secretion system modulates development, but not virulence, of the plant pathogen Streptomyces scabies.
Not available
S-EPMC6638804 | biostudies-literature
UnknownEssential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria.
Not available
S-EPMC4418733 | biostudies-literature
UnknownNew insights into the domain of unknown function (DUF) of EccC5, the pivotal ATPase providing the secretion driving force to the ESX-5 secretion system.
Not available
S-EPMC11154593 | biostudies-literature
UnknownMycobacterium tuberculosis Toxin CpnT Is an ESX-5 Substrate and Requires Three Type VII Secretion Systems for Intracellular Secretion.
Not available
S-EPMC8092274 | biostudies-literature
Genomicsppe37 mutations in Mycobacterium tuberculosis
Mutations in ppe38 block PE_PGRS secretion and cause hypervirulence in Mycobacterium tuberculosis
PRJEB14401 | ENA
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