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There is considerable evidence that inhibition of p38α mitogen-activated protein kinase diminishes cardiac damage during myocardial ischemia. During myocardial ischemia p38α interacts with TAB1, a scaffold protein, which promotes p38α autoactivation; active p38α (pp38α) then trans-phosphorylates TAB...
ORGANISM(S): Mus musculus 
Study of dynamic changes in TAK1/TAB1 complex formation after H. pylori infection in human epithelial cells
ORGANISM(S): Homo sapiens (Human) 
2017-12-06 | PXD007632 | Pride
The TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules
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