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ProteomicsHuman mitochondrial TACO1-FLAG SILAC AP-MS
The prokaryotic translation elongation factor P (EF-P), and the eukaryotic/archeal counterparts eIF5A/aIF5A, are proteins that serve a crucial role in mitigating ribosomal stalling during the translation of specific sequences, notably those containing consecutive proline residues. Although mitochond...
ORGANISM(S): Homo sapiens (Human) 
2024-09-06 | PXD051090 | Pride
Ap-ms Mitochondria Taco1 Silac 
GenomicsMitoribosome profiling (MitoRiboSeq) data from HEK293T wild-type, TACO1 knockout, and TACO1 reconstituted cells
Mitoribosome profiling (MitoRiboSeq) data from HEK293T wild-type, TACO1 knockout, and TACO1 reconstituted cells
PRJEB75695 | ENA
TranscriptomicsMitoribosome profiling (MitoRiboSeq) data from HEK293T wild-type, TACO1 knockout, and TACO1 reconstituted cells
Mitochondrial translation was investigated by mitochondrial ribosome profiling (mitoRiboSeq) in three HEK293T cell lines: HEK293T wild-type (WT), TACO1 knockout (TACO1-KO), and TACO1 reconstituted (TACO1-KO + TACO1) cells
ORGANISM(S): Homo sapiens 
2025-01-29 | E-MTAB-14071 | biostudies-arrayexpress
GenomicsStructural basis of TACO1 function in mitochondrial translation elongation
Structural basis of TACO1 function in mitochondrial translation elongation
PRJNA1332778 | ENA
TranscriptomicsStructural basis of TACO1 function in mitochondrial translation elongation
Protein synthesis depends on specialized regulatory factors to overcome difficult-to-translate sequences during elongation that cause ribosomal stalling. In human mitochondria, this function is carried out by TACO1 (Translation activator of COX1). Here, we report the cryo-electron microscopy structu...
ORGANISM(S): Homo sapiens 
2026-09-30 | GSE308835 | GEO
ProteomicsIn Situ Visualization of TACO1-Mediated Efficient Mitochondrial Translation Elongation
Isolation of CO1 mRNA ribonucleoprotein complexes from TACO1 KO and WT HEK293T cells
ORGANISM(S): Homo sapiens (Human) 
2026-01-02 | PXD064026 | Pride
Human Taco1 Mitoribosome Co1 Translation 
UnknownLoss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice.
Not available
S-EPMC4915168 | biostudies-literature
UnknownThe human mitochondrial translation factor TACO1 alleviates mitoribosome stalling at polyproline stretches.
Not available
S-EPMC11381339 | biostudies-literature
UnknownEnhanced Oxidative Phosphorylation Driven by TACO1 Mitochondrial Translocation Promotes Stemness and Cisplatin Resistance in Bladder Cancer.
Not available
S-EPMC11791945 | biostudies-literature
Genomics
The RIP-seq of TACO1-Flag compared with Vector-Flag
PRJNA953625 | ENA
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