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The unfolded protein response (UPR) helps reinstate cellular proteostasis upon an accumulation of misfolded proteins in the endoplasmic reticulum (ER), in part through ER-associated degradation (ERAD). Ube2j2 is an ER-localized E2 ubiquitin-conjugating enzyme that participates in ERAD. We used mass ...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-03 | PXD078047 | Pride
3T3 murine embryonic fibroblasts are used as feeder layers to support the proliferative potential of human primary keratinocytes during in vitro expansion for cell and gene therapy applications. To identify signals mediating this function, we analyzed fibroblast protein content using mass spectromet...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-18 | PXD078052 | Pride
MS-based proteomic analysis of the fibroblast secretome under standard-quality (SQ) and low-quality (LQ) feeder layer conditions, collected at 6 h and 16 h to characterize differences in extracellular matrix remodeling and secreted factors associated with fibroblast support of epidermal stem cell ex...
ORGANISM(S): Mus Musculus (mouse) 
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