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TranscriptomicsGene expression profiling in murine Smad-deficient CD4+ T cells stimulated with TGF-b
TGF-b is an important pleiotropic cytokine with potent immunoregulatory properties. Although many previous reports have been proposed for the immunoregulatory functions of TGF-b on T cells, such as the suppression of cell proliferation, cytokine production and cytokine signaling, as well as the indu...
ORGANISM(S): Mus musculus 
2010-07-29 | E-GEOD-19601 | biostudies-arrayexpress
TranscriptomicsPluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
To characterize the differentiation by Sox2 KO, we performed microarray analyses of mouse ES cell line 2TS22C during the time-course being induced of Sox2 KO Inducible Sox2 KO cell line 2TS22C were assigned to eight experimental groups and cultured in GMEM medium (SIGMA) with LIF at 37°C in an atmo...
ORGANISM(S): Mus musculus 
2010-06-11 | E-GEOD-5895 | biostudies-arrayexpress
TranscriptomicsEffect of ablation of Max gene expression on ES cells cultured under conventional or 2i/Nam condition.
c-Myc is one of key players that are crucially involved in maintaining the undifferentiated state and the self-renewal of ESCs. To understand the mechanism by which c-Myc helps preserve these prominent characteristics of ESCs, we generated null-ES cells for the Max gene, which encodes the best chara...
ORGANISM(S): Mus musculus 
2011-07-19 | E-GEOD-27881 | biostudies-arrayexpress
ProteomicsProteome analysis of affinity-purified protein co-precipitates
HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
ORGANISM(S): Homo Sapiens (human) 
2021-08-31 | PXD027400 | JPOST Repository
TranscriptomicsThe forced expression of Nanog or Esrrb allows preserve ESC status in the absence of nucleostemin expression
Nucleostemin (NS) gene is known to be expressed in stem cells in general including embryonic stem cells (ESCs). Previous knockdown and knockout studies have demonstrated that NS is important for the preservation of their self-renewality and high levels of pluripotent marker gene expression in mouse ...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-56797 | biostudies-arrayexpress
UnknownAurora A Exacerbates Antibiotic-Resistant Staphylococcus aureus Infection through ASC Phosphorylation
Not available
S-SCDT-10_1038-S44319-026-00918-X | biostudies-other
UnknownEarly versus delayed EUS-guided drainage for postoperative pancreatic fluid collections: a systematic review and meta-analysis.
Not available
S-EPMC10776699 | biostudies-literature
TranscriptomicsJARID2-associated protein network drives rapid and efficient reprogramming to pluripotency.
Somatic cell reprogramming can be achieved by cell fusion with embryonic stem cells (ESCs), nuclear transfer into oocytes, or forced expression of transcription factors essential for ESC identity. Reprogramming by transcription factors is a less efficient and slower process than that by other method...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-52200 | biostudies-arrayexpress
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