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ProteomicsExtensive proteomic approaches to identify glycosylphosphatidylinositol-anchored proteins in Arabidopsis reveal their diverse responses to cold acclimation
When plants are exposed to non-freezing low temperatures, they can increase their freezing tolerance (cold acclimation, CA). Changes of plasma membrane (PM) and sterol/sphingolipid-enriched microdomain proteins are thought to be crucial for acquisition of freezing tolerance. Particularly, glycosylph...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2016-07-29 | PXD002908 | Pride
Arabidopsis Plasma membrane Detergent-resistant membrane Microdomain Gpi-anchored protein Apoplast Freezing tolerance Cold acclimation 
TranscriptomicsDevelopment of gene expression signatures for miR-340 overexpressing human glioma-initiating cells (GICs)
To identify functional targets of miR-340, we compared the gene expression profiles of miR-340 overexpressing human GICs with the profiles of their parental cells. The precursor form of miR-340 or control miRNA was overexpressed in glioma cells using miRNA lentiviral particles. The cells were incuba...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-61078 | biostudies-arrayexpress
TranscriptomicsDevelopment of microRNA (miRNA) expression signatures for human glioma-initiating cells (GICs)
To identify a novel miRNA that is aberrantly expressed in GICs, we analyzed differences in miRNA expression between the human GICs and glioma cell lines and neural stem cells by miRNA microarrays. We examined the miRNA expression profiles of five human GICs that were obtained from human glioma sampl...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-61079 | biostudies-arrayexpress
TranscriptomicsDevelopment of microRNA (miRNA) expression signatures for mouse glioma-initiating cells (GICs)
To identify a novel miRNA that is aberrantly expressed in GICs, we analyzed differences in miRNA expression between the mouse GICs, NSCL61 and OPCL61, showing characteristic features of cancer stem cell, and their parental cells by miRNA microarrays. neural stem cells, glioma-initiating cells (GICs)...
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-61080 | biostudies-arrayexpress
TranscriptomicsIsolation of human iPSC-derived dopaminergic progenitors by cell sorting
Human induced pluripotent stem cells (iPSCs) can provide a promising source of midbrain dopaminergic (DA) neurons for cell replacement therapy for Parkinson’s disease. However, iPSC-derived donor cells may inevitably contain tumorigenic or inappropriate cells. Purification of neural progenitor cells...
ORGANISM(S): Homo sapiens 
2014-03-07 | E-GEOD-51214 | biostudies-arrayexpress
TranscriptomicsPluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
To characterize the differentiation by Sox2 KO, we performed microarray analyses of mouse ES cell line 2TS22C during the time-course being induced of Sox2 KO Inducible Sox2 KO cell line 2TS22C were assigned to eight experimental groups and cultured in GMEM medium (SIGMA) with LIF at 37°C in an atmo...
ORGANISM(S): Mus musculus 
2010-06-11 | E-GEOD-5895 | biostudies-arrayexpress
TranscriptomicsDownregulation of microRNA-132 is associated with liver metastasis of colorectal cancer by targeting Anoctamin 1.
In this study, we conducted a microarray-based analysis to identify differentially expressed miRNAs in CRC by comparing miRNA profiles among primary CRC tissues from patients with liver metastases, primary tissues without liver metastases, and liver metastatic lesions. microRNAs (miRNAs) have been s...
ORGANISM(S): Homo sapiens 
2016-02-14 | E-GEOD-72199 | biostudies-arrayexpress
ProteomicsKSN01_Proteome_CellLine: Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H
Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H
ORGANISM(S): Homo Sapiens (human) 
2020-12-15 | PXD010107 | JPOST Repository
ProteomicsSerum proteome profiling of patients with non-small cell lung cancer treated with immune checkpoint blockade monotherapy
Shotgun proteomic profiling of serum from patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint blockade (ICB) monotherapy. Top-14 abundant proteins were depleted (Pierce High-Select, Thermo Fisher Scientific), and tryptic digests were spiked with the Pierce Peptide Retenti...
ORGANISM(S): Homo Sapiens (human) 
2026-06-10 | PXD078247 | JPOST Repository
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