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Androgen receptor (AR) is overexpressed in the majority of castration-resistant prostate cancers (CRPCs). Our goal was to study the effect of AR overexpression on the chromatin binding of the receptor and to identify AR target genes that may be important in the emergence of CRPC. We have established...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
miRNA expression profiling of prostate cancer cell lines, PC-3, DU145, LAPC-4, VCaP, LNCaP, 22rv1, and normal prostate epithelial cells, PrECs, was done after treating the cells with DNA demethylating agent 5-aza-2'-deoxycytidine (5azadC; Sigma-Aldrich, St. Louis, MO) and histone deacetylase inhibit...
ORGANISM(S): Homo sapiens 
miRNA expression profiling of 13 clinical prostate samples, 4 benign prostate hyperplasias, 5 untreated primary prostate carcinomas and 4 castration-resistant prostate cancers.
ORGANISM(S): Homo sapiens 
miRNA expression profiling in 6 prostate cancer cell lines, 9 prostate cancer xenografts, and 13 clinical prostate tumor samples
ORGANISM(S): Homo sapiens 
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