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TranscriptomicsExpression data of Hepatocellular Carcinoma
Expression profiling of Xenografts of Hepatocellular Carcinoma Keywords: Human Cancer Briefly, primary HCCs obtained during liver resection were minced into fine fragments capable of passing through an 18-gauge needle, mixed in a 1:1 (v/v) ratio with Matrigel (Collaborative Research, Bedford, MA) an...
ORGANISM(S): Homo sapiens 
2008-11-01 | E-GEOD-6465 | biostudies-arrayexpress
TranscriptomicsGEMINI (Gastric Encyclopedia of Molecular Interactions and Nodes for Intervention) Phases A-C
Genome-wide mRNA expression profiles of 25 unique gastric cancer cell lines (GCCLs). Gastric cancer (GC) is the second leading cause of global cancer mortality, with individual gastric tumors displaying significant heterogeneity in their deregulation of various oncogenic pathways. We aim to identify...
ORGANISM(S): Homo sapiens 
2009-10-06 | E-GEOD-15455 | biostudies-arrayexpress
TranscriptomicsGEMINI (Gastric Encyclopedia of Molecular Interactions and Nodes for Intervention) Phases A-C, normal skin fibroblasts
Genome-wide mRNA expression profiles of normal skin fibroblasts, used as one of the (normal) references in the study. Gastric cancer (GC) is the second leading cause of global cancer mortality, with individual gastric tumors displaying significant heterogeneity in their deregulation of various oncog...
ORGANISM(S): Homo sapiens 
2009-10-06 | E-GEOD-15537 | biostudies-arrayexpress
TranscriptomicsEpigenetic analysis of gastric cancer cell lines
Genome wide DNA methylation profiling of gastric cancer cell lines. The Illumina Goldengate DNA methylation Beadchip was used to obtain DNA methylation profiles across 1,505 CpG CpGs in 20 gastric cancer cell lines. Bisulphite converted DNA from the 20 gastric cancer cell lines were hybridised to th...
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-29499 | biostudies-arrayexpress
GenomicsDAC for Duke-NUS genomic sequencing projects
Data Access Committee EGAC00001000256
EGAC00001000256 | EGA
TranscriptomicsEpigenetic analysis of gastric cancer
Genome-wide DNA methylation profiling of gastric tumors and matched gastric non-malignant samples. The Illumina HumanMethylation27 BeadChip was used to obtain DNA methylation profiles across 27,578 CpGs in 203 gastric tumors and 94 matched non-malignant gastric samples. Bisulphite-converted DNA fro...
ORGANISM(S): Homo sapiens 
2012-10-24 | E-GEOD-30601 | biostudies-arrayexpress
TranscriptomicsGenetic Landscape of Copy Number Alterations in Gastric Cancer
Genome-wide DNA copy number profiling of gastric tumors and matched non-maligant samples. The affymetrix SNP6 array was used to obtain DNA copy number profiles in 193 gastric tumors and 98 matched gastric non-malignant samples. Genomic DNA extracted from 193 gastric tumors and 98 matched gastric non...
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-31168 | biostudies-arrayexpress
TranscriptomicsGastric Cancer Cell Lines
Regions of recurrent genomic amplification and deletion are frequently observed in primary gastric cancers (GC). However, identifying specific oncogenes and tumor suppressor genes within these regions can be challenging, as they often cover tens to hundreds of genes. Here, we combined high-resolutio...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-10611 | biostudies-arrayexpress
GenomicsNanoscale Chromatin Profiling of Gastric Adenocarcinoma
To identify chromatin alterations in primary gastric adenocarcionomas, we performed nano-scale chromatin immunoprecipitation-sequencing (Nano-CHiPseq) of histone modifications in 5 gastric cancers and matched normal tissues, We identified hundreds of somatically-altered promoters (marked by H3K4me3)...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-51776 | biostudies-arrayexpress
TranscriptomicsGastric cancer subtyping (Singapore Patient Cohort, batch B)
Genome-wide mRNA expression profiles of 56 primary gastric tumors from the Singapore patient cohort, batch B. Like many cancers, gastric adenocarcinomas (gastric cancers) show considerable heterogeneity between patients. Thus, there is intense interest in using gene expression profiles to discover s...
ORGANISM(S): Homo sapiens 
2014-09-05 | E-GEOD-34942 | biostudies-arrayexpress
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