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TranscriptomicsTranscriptome analysis of zebrafish heart exposed to sorafenib
Sorafenib is associated with cardiac adverse effects, including left ventricular dysfunction. However, the precise mechanism remains unclear. Here, we aimed to establish the genes responsible for this cardiotoxicity using zebrafish. A pigmentless zebrafish line expressing green fluorescent protein i...
ORGANISM(S): Danio rerio 
2014-12-04 | E-GEOD-61155 | biostudies-arrayexpress
TranscriptomicsExpression data from Fbxl10 overexpressing 3T3-L1 cells
Target genes of Fbxl10 during 3T3-L1 adipogenesis was analyzed 3T3-L1 cells overexpressing Fbxl10 using retrovirus system containing LTR promoter were differentiated and RNA was extracted at day 2 of differentiation
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-64154 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of diet induced obesity model zebrafish
As microarray based gene expression profiling is well suited to study the complex diseases such as obesity, we revealed gene expression changes of fat tissues on obesity model zebrafish to elcidate the pathophysiological function of each fat tissue in metabolic syndrome. Zebrafish in over-feeding gr...
ORGANISM(S): Danio rerio 
2010-10-12 | E-GEOD-18566 | biostudies-arrayexpress
Proteomics,MultiomicsHematopoietic stem cells (HSCs)
G0 marker-separation of dormant and active hematopoietic stem cells reveals dormancy regulation by basal cytoplasmic calcium
ORGANISM(S): Mus Musculus (mouse) 
2019-12-19 | PXD012093 | JPOST Repository
TranscriptomicsDNA microarray analysis of labial salivary glands in IgG4-related disease M-bM-^@M-^S comparison with SjM-CM-6grenM-bM-^@M-^Ys syndrome
To compare gene expression in labial salivary glands (LSG) of IgG4-related disease (IgG4-RD) with SjM-CM-6grenM-bM-^@M-^Ys syndrome (SS). Gene expression was analyzed by DNA microarray in LSG of IgG4-RD (n=5), SS (n=5), and healthy controls (n=3). Differentially expressed genes...
ORGANISM(S): Homo sapiens 
2014-06-23 | E-GEOD-40568 | biostudies-arrayexpress
TranscriptomicsLife span-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans
One of the most important issues in the study of aging is to discover compounds with longevity-promoting activity and to unravel their underlying mechanisms. Queen honey bees are continuously fed royal jelly (RJ), and they live more than 10 times longer than hive workers, derived from the same diplo...
ORGANISM(S): Caenorhabditis elegans 
2011-07-21 | E-GEOD-26094 | biostudies-arrayexpress
TranscriptomicsInduced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery
Chronic infantile neurological cutaneous and articular (CINCA) syndrome is an IL-1-driven autoinflammatory disorder caused mainly by NLRP3 mutations. The pathogenesis of CINCA syndrome patients who carry NLRP3 mutations as somatic mosaicism has not been precisely described because of the difficulty ...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-38626 | biostudies-arrayexpress
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