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ProteomicsProteomics analysis of blood neutrophils from WT and Wnt5 DKO mice under DSS treatment
Neutrophils are abundant innate immune cells with important roles in host defense and many inflammatory diseases. They possess plasticity and heterogenicity, which underlie their functional ambivalency; they can be beneficial or detrimental to host well-being depending on contexts. While bone marrow...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-16 | PXD048613 | Pride
Wnt5 Neutrophil Proteomics Dia 
ProteomicsProteomic analysis of the physiological E3 ubiquitin ligase responsible for PIN1 degradation
Induced oncoproteins degradation provides an attractive anti-cancer modality. Activation of anaphase-promoting complex (APC/CCDH1) prevents cell cycle entry by targeting crucial mitotic proteins for degradation. Phosphorylation of its co-activator CDH1 modulates the E3 ligase activity, but little is...
ORGANISM(S): Homo sapiens (Human) 
2024-02-28 | PXD046325 | Pride
Pin1 Proteomics Cdh1 
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