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Intervertebral Disc (IVD) degeneration leading to Low back pain (LBP) is the most common musculoskeletal disorder. Lack of knowledge on the intricate homeostatic mechanisms necessitates proteomic characterisation of a normal human IVD to understand the biological process and unravel the pathomechani...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD016560 | Pride
Intervertebral disc (IVD) degeneration is a leading contributor to chronic low back pain, a condition with significant socioeconomic and healthcare burdens worldwide. Despite its prevalence, early diagnosis and effective, targeted therapies for IVD degeneration remain limited, largely due to an inco...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD063403 | Pride
Research on disc degeneration has been heterogeneous in their use of control discs used for comparison with diseased discs. Discs from scoliosis, cadavers and voluntary organ donors are the common controls used in intervertebral disc research. In order to find out the ideal control among these discs...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD018968 | Pride
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