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TranscriptomicsGenome-wide location analysis of Dnmt3a-mediated epigenetic regulation in murine postnatal subventricular zone (SVZ) neural stem cells (NSCs) [NimbleGen]
DNA methylation at proximal promoters facilitates lineage restriction by silencing cell-type specific genes. However, euchromatic DNA methylation frequently occurs in regions outside promoters. The functions of such non-proximal promoter DNA methylation are unclear. Here we show that the de novo DNA...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-22475 | biostudies-arrayexpress
TranscriptomicsThe differentially expressed genes of Zucker Diabetic Fatty Rats treated with Berberine against diabetes mellitus
The anti-diabetes activity of Rhizoma Coptidis was documented in the book “Notes of Elite Physicians” written by Hongjing Tao 1500 years ago. Berberine (BBR) is the major isoquinoline alkaloid constituent of the Chinese herb Rhizoma Coptidis, which has the beneficial characteristic of regulating...
ORGANISM(S): Rattus norvegicus 
2016-11-30 | E-MTAB-5178 | biostudies-arrayexpress
Transcriptomicsβ-cateinin activation in hair follicle dermal sheath induces ectopic hair outgrowth and skin fibrosis
Dermal sheath (DS) shows potent hair inducing capability and high plasticity without leading to immuno rejection. A recent study showed a subset of DS cells, identified as hair follicle (HF) dermal stem cells, can be mobilized to regenerate DS, maintain/supply the cell number of dermal papilla (DP) ...
ORGANISM(S): Mus musculus 
2016-05-31 | E-GEOD-81615 | biostudies-arrayexpress
TranscriptomicsDnmt3a-dependent non-promoter DNA methylation facilitates transcription of neurogenic genes
This SuperSeries is composed of the following subset Series: GSE22473: Murine postnatal subventricular zone (SVZ) neural stem cells (NSCs): Wild-type (WT) vs. Dnmt3a-null (KO) GSE22474: Genome-wide location analysis of Dnmt3a-mediated epigenetic regulation in murine postnatal subventricular zone (SV...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-22476 | biostudies-arrayexpress
UnknownIncreased plasma genistein after bariatric surgery could promote remission of NAFLD in patients with obesity.
Not available
S-EPMC9846086 | biostudies-literature
ProteomicsHuman protein phosphorylation analysis
Mycobacterium tuberculosis (Mtb) protein kinase G (PknG) is a critical protein which can inhibit the maturation of phagosome and its fusion with the lysosome, providing Mtb’s latency and survival in the host. However, its signaling pathways and functions in the human body are still unclear and neede...
ORGANISM(S): Homo sapiens (Human) 
2018-10-10 | PXD009237 | Pride
Phosphorylation Human 
UnknownPrognostic and predictive value of radiomic signature in stage I lung adenocarcinomas following complete lobectomy.
Not available
S-EPMC9331779 | biostudies-literature
Other,MultiomicsChevrette et al 2019 Insect-associated Streptomyces
Paper title: The antimicrobial potential of Streptomyces from insect microbiomes. Author list: Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo ...
ORGANISM(S): Pseudonocardia Kitasatospora Streptomyces Gordonia <actinomycete> 
2019-12-18 | MSV000084723 | MassIVE
UnknownMolecular basis of neurovirulence of flury rabies virus vaccine strains: importance of the polymerase and the glycoprotein R333Q mutation.
Not available
S-EPMC2919041 | biostudies-literature
TranscriptomicsGenome-wide Analysis Reveals Mecp2-dependent Regulation of MicroRNAs in a Mouse Model of Rett Syndrome (mm8 tiling array)
MicroRNAs (miRNAs) are a class of small non-coding RNAs that function as post-transcriptional regulators of gene expression. Many miRNAs are expressed in the developing brain and regulate multiple aspects of neural development including neurogenesis, dendritogenesis and synapse formation. Rett syndr...
ORGANISM(S): Mus musculus 
2010-09-30 | E-GEOD-24285 | biostudies-arrayexpress
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