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CDK9 is a critical kinase required for the productive transcription of protein-coding genes by RNA polymerase II (pol II) in higher eukaryotes. Phosphorylation of targets including the elongation factor SPT5 and the carboxyl-terminal domain (CTD) of RNA pol II allow the polymerase to pass an early e...
ORGANISM(S): Homo sapiens (Human) 
2022-08-22 | PXD026720 | Pride
ADP-ribosylation (ADPr) is a reversible modification of macromolecules critical for the regulation of genome stability, stress responses, and proteostasis. While the roles of ADPr transferases such as PARP1/2 and TNKS1/2 are well established, the cellular functions and regulatory mechanisms of ADPr ...
ORGANISM(S): Homo sapiens (Human) 
2026-01-02 | PXD065407 | Pride
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