Telomere binding protein

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Unknown (657)
Transcriptomics (596)
Genomics (247)
Proteomics (43)
Other (5)
Metabolomics (5)

Organisms

Homo sapiens (265)
Mus musculus (186)
Drosophila melanogaster (71)
Schizosaccharomyces pombe (60)
Saccharomyces cerevisiae (60)
Arabidopsis thaliana (23)
Rattus norvegicus (8)
Neisseria gonorrhoeae (5)
Neisseria meningitidis (5)
Bos taurus (5)
Caenorhabditis elegans (5)
Zea mays (4)
Candida albicans (4)
Danio rerio (4)
Saccharomyces cerevisiae SK1 (3)
Anopheles gambiae (3)
Oncorhynchus mykiss (3)
Heterocephalus glaber (3)
Gallus gallus (3)
Caulobacter vibrioides (2)
Bacillus subtilis subsp. subtilis str. 168 (2)
Macaca mulatta (2)
Papio hamadryas (2)
Oryza sativa (2)
mixed sample (2)
Saccharomyces cerevisiae S288C (2)
Klebsiella pneumoniae (2)
Ovis aries (2)
Cryptococcus neoformans (2)
Escherichia coli str. K-12 substr. MG1655 (2)

Organisms

Homo sapiens (25)
Mus musculus (15)
Saccharomyces cerevisiae (7)
Schizosaccharomyces pombe (7)
Arabidopsis thaliana (6)
Drosophila melanogaster (5)
Stylonychia lemnae (2)
Trypanosoma brucei brucei (2)
Neurospora crassa (2)
Fusarium graminearum PH-1 (1)
Plasmodium falciparum 3D7 (1)
Plasmodium falciparum (1)
Caenorhabditis elegans (1)
Rattus norvegicus (1)

Repository

biostudies-arrayexpress (674)
ENA (88)
geo (70)
pride (37)
EGA (18)
MetaboLights (5)
MassIVE (4)
iProX (1)
PeptideAtlas (1)

Tissue

Cell culture (13)
Breast (2)
Plant cell (2)
Others (1)
BA/F3 cell (1)
Bone marrow (1)
Bone tissue (1)
Diploid cell (1)
Early embryonic cell (1)
Epithelial cell (1)
Fibroblast (1)
HeLa cell (1)
Testis (1)

Disease

Osteosarcoma (5)
Normal (4)
Colorectal cancer (2)
Breast cancer (2)
Chronic lymphocytic leukemia (CLL) (1)
T. circumcincta infection (1)
Post-stasis (1)
IV (1)
Megakaryoblastic leukaemia (1)
Cancer (1)
Obesity (1)
S enteritidis (1)
Disease free (1)
Polycystic Kidney (1)

Technology Type

Mass Spectrometry (37)
Shotgun proteomics (13)
Affinity purification coupled with mass spectrometry proteomics (12)
Gel-based experiment (9)
Bottom-up proteomics (8)
Data-dependent acquisition (6)
Mass spectrometry (3)
Data-independent acquisition (3)
NMR spectroscopy (1)
NMR spectroscopy assay (1)
SWATH MS (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (20)
NextSeq 500 (17)
Illumina HiSeq 2500 (16)
Illumina HiSeq 2000 (9)
Illumina HiSeq 4000 (7)
ScanArray Express HT (4)
Axon GenePix 4000B scanning hardware (4)
Vortex (4)
Illumina MiSeq (4)
Illumina HiSeq 1500 (3)
NextSeq 550 (3)
PromethION (2)
Other (2)
GenePix 4000A [Axon Instruments] (2)
Scanning hardware (2)
HiSeq X Ten (2)
DNBSEQ Eukaryotic Stranded Transcriptome library preparation- Stranded mRNA Library (1)
Pacbio Revio (1)
FastPrep-24 5G bead beater, Qubit Fluorometer (1)
12 well TC-treated plate, LETs buffer, dry ice (1)
IEO HPC (1)
Axon GenePix4000B (1)
Agilent Scanner (1)
IPstar-compact (diagenode) (1)
ScanArray 5000 [PerkinElmer] (1)
Illumina Genome Analyzer IIx (1)
Axon- GenePix4000B (1)
G2565BA DNA microarray scanner [Agilent] (1)
ScanArray Express HT [PerkinElmer] (1)
GenePix 4000B [Axon Instruments] (1)

Publication Date

2013 (91)
2011 (89)
2010 (85)
2016 (58)
2015 (58)
2012 (48)
2009 (47)
2014 (38)
2024 (34)
2026 (31)
2008 (28)
2007 (23)
2023 (22)
2021 (19)
2020 (19)
2004 (19)
2022 (15)
2017 (15)
2006 (13)
2025 (12)
2018 (12)
2005 (9)
2019 (7)

UNIPROT ID/AC

A0A024RC46 (1)
A0A087WTX5 (1)
A0A087WUD1 (1)
A0A087WVW2 (1)
A0A087WXI0 (1)
A0A087WYL9 (1)
A0A087X130 (1)
A0A087X1V9 (1)
A0A0A0MR66 (1)
A0A0A0MS07 (1)
A0A0A0MS51 (1)
A0A0B4J220 (1)
A0A0C4DG89 (1)
A0FGR8 (1)
A0FGR8-2 (1)
A0FGR8-6 (1)
A0M8Q6 (1)
A1L170 (1)
A2NUT2 (1)
A4D110 (1)
A4F255 (1)
A5A3E0 (1)
A6NCN2 (1)
A6NHL2 (1)
A6NHQ2 (1)
A6NHR9 (1)
A6NL93 (1)
A6NNZ2 (1)
A7E2Y1 (1)
A8K2U0 (1)

ENSEMBL ID

ENSG00000170477 (1)

CHEBI ID

CHEBI:15428 (3)
CHEBI:16449 (3)
CHEBI:16737 (3)
CHEBI:16742 (3)
CHEBI:16919 (3)
CHEBI:16958 (3)
CHEBI:17750 (3)
CHEBI:27266 (3)
CHEBI:28300 (3)
CHEBI:30769 (3)
CHEBI:32816 (3)
CHEBI:15354 (2)
CHEBI:15356 (2)
CHEBI:15611 (2)
CHEBI:15676 (2)
CHEBI:15724 (2)
CHEBI:15741 (2)
CHEBI:15891 (2)
CHEBI:15978 (2)
CHEBI:15999 (2)
CHEBI:16040 (2)
CHEBI:16335 (2)
CHEBI:16344 (2)
CHEBI:16411 (2)
CHEBI:16450 (2)
CHEBI:16708 (2)
CHEBI:16750 (2)
CHEBI:16797 (2)
CHEBI:16811 (2)
CHEBI:17154 (2)

Metabolite Name

Adenine (2)
Beta-alanine (2)
Betaine (2)
Citrate (2)
Creatine (2)
Creatinine (2)
Glucose (2)
Guanosine (2)
Hypoxanthine (2)
Pyruvate (2)
Succinate (2)
Taurine (2)
(2R)-2,3-Dihydroxypropanoic acid (1)
(R)-3-hydroxybutyrylcarnitine (1)
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPC (P-16:0/20:4)* (1)
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPE (P-16:0/20:4)* (1)
1-(1-enyl-palmitoyl)-2-linoleoyl-GPC (P-16:0/18:2)* (1)
1-(1-enyl-palmitoyl)-2-linoleoyl-GPE (P-16:0/18:2)* (1)
1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1)* (1)
1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0)* (1)
1-(1-enyl-palmitoyl)-GPE (P-16:0)* (1)
1-(1-enyl-stearoyl)-2-linoleoyl-GPE (P-18:0/18:2)* (1)
1-(1-enyl-stearoyl)-GPE (P-18:0)* (1)
1-arachidonoyl-GPA (20:4) (1)
1-arachidonoyl-GPI (20:4)* (1)
1-lignoceroyl-GPC (24:0) (1)
1-linolenoyl-GPC (18:3)* (1)
1-linoleoyl-2-arachidonoyl-GPC (18:2/20:4n6)* (1)
1-linoleoyl-GPA (18:2)* (1)
1-linoleoyl-GPC (18:2) (1)

First Public Date

2024 (20)
2014 (15)
2026 (9)
2017 (8)
2025 (6)
2023 (5)
2022 (4)
2018 (4)
2016 (4)
2015 (4)
2021 (3)
2020 (2)
2019 (2)
2013 (2)

Classification

protozoa (4)
fungi (1)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (295)
ChIP-seq (88)
ChIP-chip by tiling array (68)
RNA-seq of coding RNA (58)
ChIP-chip by array (25)
Comparative genomic hybridization by array (19)
Methylation profiling by array (18)
Other (16)
Unknown experiment type (13)
Methylation profiling by high throughput sequencing (13)
DNA-seq (9)
RNA-seq of coding RNA from single cells (8)
RNA-seq of non coding RNA (5)
Cell line - High-throughput sequencing (4)
High-throughput sequencing (3)
CLIP-seq (3)
RNA-seq of total RNA (3)
Animal - High-throughput sequencing (2)
Transcription profiling by tiling array (2)
4C (2)
RIP-seq (2)
MicroRNA profiling by array (2)
CUT&RUN (2)
FAIRE-seq (1)
Transcription profiling by SAGE (1)
RIP-chip by array (1)
Animal - One-color microarray (1)
Human - Single-cell sequencing (1)
Human - High-throughput sequencing (1)
RNAi profiling by array (1)

Release Date

2013 (113)
2011 (111)
2010 (108)
2016 (88)
2015 (84)
2014 (78)
2012 (78)
2009 (71)
2021 (59)
2022 (55)
2020 (53)
2023 (50)
2017 (45)
2008 (45)
2024 (44)
2018 (43)
2025 (38)
2007 (36)
2019 (29)
2004 (25)
2005 (21)
2006 (20)
2026 (19)
2003 (5)
1999 (5)
2001 (4)
2002 (1)
2000 (1)
1997 (1)

Lab affiliation

Institute of Molecular Biology (IMB) (3)
Basic Immune System of Plants / Protein Mass Spectrometry Max Planck Institute for Plant Breeding Research Carl-von-Linne-Weg 10, 50829 Cologne, Germany (2)
Cancer Science Institute of Singapore (CSI), National University of Singapore (NUS) (2)
Cancer Science Institute of Singapore (CSI), National University of Singapore (NUS (1)
Cancer Science Institute, National University of Singapore, Singapore (1)
Case Comprehensive Cancer Center, Case Western Reserve University, USA (1)
Centre to Impact AMR, Monash University; Clayton, 3800, Australia Infection Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University; Clayton, 3800, Australia (1)
Charité Universitätsmedizin Berlin, Germany (1)
Children's Medical Research Institute. Telomere Length Regulation Unit. (1)
Department of Biology University of York Heslington York YO10 5DD (1)
Department of Chemistry, University of California Riverside (1)
Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403. (1)
Department of Molecular Mechanisms of Disease, University of Zurich (UZH), Zurich, Switzerland (1)
Dept.Pharmacology & Chemical Biology UPMC Hillman Cancer Center (1)
Dr. Jeremy Balsbaugh, Proteomics & Metabolomics Facility, Center for Open Research Resources & Equipment University of Connecticut Storrs, CT 06269 (1)
Functional Proteomics Lab, Department of Life Sciences, University of Siena, 53100 Siena, Italy (1)
IMB, Ackermannweg 4, 55128 Mainz (1)
IRIC-Université de Montréal (1)
ITQB NOVA, Oeiras, Portugal (1)
Institute of Molecular Biology (IMB) Ackermannweg 4 55128 Mainz (1)
Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz (1)
Institute of Molecular Biology Ackermannweg 4 55128 Mainz (1)
Institute of Molecular and Cellular Biology, National Taiwan University, No. 1 Sec. 4 Roosevelt Road, Taipei, Taiwan (1)
Medical Research Council - London Institute of Medical Sciences, Telomere Replication and Stability Group, United Kingdom. (1)
Proteomics and Metabolomics Core Facility, Department of Cancer Biology, The Institute of Cancer Research, London, UK. (1)
Quantitative Proteomics Institute of Molecular Biology (IMB) (1)
Research Institute for Microbial Diseases (1)
Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield S10 2HQ, United Kingdom (1)
State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei 430062, China (1)
The University of Edinburgh (1)

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The telomere-binding protein Tbf1 demarcates snoRNA gene promoters in Saccharomyces cerevisiae

The majority of Saccharomyces cerevisiae snoRNA promoters contain an aRCCCTaa sequence motif located at the upstream border of a TATA-containing nucleosome-free region. Genome-wide ChIP-seq analysis showed that these motifs are bound in vivo by Tbf1, a telomere-binding protein known to recognize mam...

ORGANISM(S): Saccharomyces cerevisiae

2010-05-28 | E-GEOD-20870 | biostudies-arrayexpress

Telomeric repeats facilitate CENP-A incorporation via telomere binding proteins

The histone H3 variant, CENP-ACnp1, is normally assembled upon canonical centromeric sequences, but there is no apparent obligate coupling of sequence and assembly, suggesting that centromere location can be epigenetically determined. To explore the tolerances and constraints on CENP-ACnp1 depositio...

ORGANISM(S): Schizosaccharomyces pombe

2013-08-22 | E-GEOD-46427 | biostudies-arrayexpress

Telomere dysfunction and fusion during the progression of chronic lymphocytic leukaemia: evidence for a telomere crisis

We performed single-molecule telomere length and telomere fusion analysis in patients at different stages of chronic lymphocytic leukaemia (CLL). Our work identified the shortest telomeres ever recorded in primary human tissue reinforcing the concept that there is significant cell division in CLL. F...

ORGANISM(S): Homo sapiens

2010-05-28 | E-GEOD-22016 | biostudies-arrayexpress

Telomere length effect on genes near the telomere in myoblasts

We examined differential expression of genes within 10MBs of telomeres in myoblasts with long or short telomeres We offer telomere looping with telomere length as a partial mechanistic explanation for the changes gene expression that is observed. Compare expression of genes within 10MB of the telome...

ORGANISM(S): Homo sapiens

2014-07-17 | E-GEOD-48973 | biostudies-arrayexpress

Telomere Binding Protein TRB1 Preferentially Associates with Promoters of Translation Machinery genes

Background: Recently we characterised TRB1, a protein from a single-myb-histone family, as a structural and functional component of telomeres in Arabidopsis thaliana. TRB proteins, besides their ability to bind specifically telomeric DNA using their N-terminally positioned myb-like domain of the sam...

ORGANISM(S): Arabidopsis thaliana

2015-12-21 | E-GEOD-69431 | biostudies-arrayexpress

Distinctions between the stasis and telomere attrition senescence barriers in cultured human mammary epithelial cells

Molecular distinctions between the stasis and telomere attrition senescence barriers in cultured human mammary epithelial cells Normal human epithelial cells in culture have generally shown a limited proliferative potential of ~10-40 population doublings before encountering a stress-associated sene...

ORGANISM(S): Homo sapiens

2010-05-28 | E-GEOD-16058 | biostudies-arrayexpress

DVE-1 is a telomere-binding protein and links the NuRD complex to telomere regulation in C. elegans

PRJNA1471620 | ENA

Transcription profiling of acute telomere dysfunction in the mouse liver using adenoviral mediated, transient expression of a dominant negative version of TRF

Telomere dysfunction induces two types of cellular responses: cellular senescence and apoptosis. Here we analyzed the influence of the cellular level of telomere dysfunction and the role of p53 on induction of apoptosis and senescence in mouse liver using the experimental system of adenoviral mediat...

ORGANISM(S): Mus musculus

2006-11-21 | E-MEXP-141 | biostudies-arrayexpress

DVE-1 is telomere-binding protein and links the NuRD complex to telomere regulation in C.elegans

Telomeres comprise repetitive DNA sequences bound by specialized proteins at the end of linear chromosomes. Although some proteins have been identified and characterized in the nematode Caenorhabditis elegans, additional remain to be discovered, validated, and characterized. In our previous quantita...

ORGANISM(S): Caenorhabditis elegans

2026-06-15 | PXD069391 | Pride

Lc-ms/ms

Identification of telomere-binding proteins by enChIP-MS

We identified the telomere associated molecules by engineered DNA-binding molecule-mediated chromatin immunoprecipitaion (enChIP). Purified proteins were analyzed by GeLC-MS/MS. Tandem mass spectra were extracted by Proteome Discoverer 1.2. Database searchs were submitted to an in-house Mascot serve...

ORGANISM(S): Mus musculus (Mouse)

2013-11-12 | PXD000461 | Pride

Mouse Telomere binding protein Lc-ms/ms

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1555 Results

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