Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos, instrument model
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Ba/f3 Cell
SUBMITTER: Kazunobu Saito
PROVIDER: PXD000461 | Pride | 2013-11-12
REPOSITORIES: Pride
Fujita Toshitsugu T Asano Yoshinori Y Ohtsuka Junko J Takada Yoko Y Saito Kazunobu K Ohki Rieko R Fujii Hodaka H
Scientific reports 20131108
Biochemical analysis of molecular interactions in specific genomic regions requires their isolation while retaining molecular interactions in vivo. Here, we report isolation of telomeres by engineered DNA-binding molecule-mediated chromatin immunoprecipitation (enChIP) using a transcription activator-like (TAL) protein recognizing telomere repeats. Telomeres recognized by the tagged TAL protein were immunoprecipitated with an antibody against the tag and subjected to identification of telomere-b ...[more]