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ProteomicsFoxp3 positive and negative cell comparison
Regulatory T cells have been shown to adopt a catabolic metabolic programme with increased capacity for fatty acid oxidation fuelled oxidative phosphorylation (OXPHOS). The role of Foxp3 in this metabolic shift is poorly understood. Here we show that Foxp3 was sufficient to induce a significant incr...
ORGANISM(S): Mus musculus (Mouse) 
2017-02-15 | PXD001789 | Pride
Mouse t cells 
ProteomicsHuman Treg LC-MSMS - Foxp3 drives oxidative phosphorylation and protection from lipotoxicity
Regulatory T cells (Treg) have been shown to adopt a catabolic metabolic programme with increased capacity for fatty acid oxidation fuelled oxidative phosphorylation (OXPHOS). The role of Foxp3 in this metabolic shift is poorly understood. Here we show that Foxp3 was sufficient to induce a significa...
ORGANISM(S): Homo sapiens (Human) 
2017-02-15 | PXD001906 | Pride
Human t cell treg foxp3 lc-msms 
UnknownMeta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
Not available
S-EPMC4863040 | biostudies-literature
ProteomicsA Protein Deep Sequencing Evaluation of Metastatic Melanoma Tissues, unfractionated approach
Malignant melanoma has currently the highest increase of incidence of malignancies in the western world. In early stages, front line therapy is surgical excision of the primary tumor. Metastatic disease has previously has very limited possibilities to be cured. Recently, several protein kinase inhib...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-23 | MSV000080280 | MassIVE
Transcriptomics454 Life Sciences/Roche and Illumina sequencing of small RNAs from planarian samples
Freshwater planarian flatworms possess uncanny regenerative capacities mediated by abundant and collectively totipotent adult stem cells. Key functions of these cells during regeneration and tissue homeostasis have been shown to depend on PIWI, a molecule required for piRNA expression in planarians....
ORGANISM(S): Schmidtea mediterranea 
2009-06-30 | E-GEOD-16159 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast under conditions of ammonium, L-alanine or L-glutamine limitation
Response of Saccharomyces cerevisiae to Ammonium, L-alanine, or L-glutamine Limitation. The protrotophic laboratory strain CEN.PK113-7D (MAT a) was grown in laboratory fermentors with a working volume of 1 litre at dilution rate (D) of 0.20 per hour (in triplicate for each nitrogen limited condition...
ORGANISM(S): Saccharomyces cerevisiae 
2006-06-13 | E-MEXP-724 | biostudies-arrayexpress
OtherA Protein Deep Sequencing Evaluation of Metastatic Melanoma Tissues.
Data from ProteomeXchange, .PXD ID: PXD001724. Experiment: M35_003, file: folder summary. Published as part of PLoS One. 2015 Apr 13;10(4):e0123661 . From the Abstract: {{i}} ... The aim of the present study was to build a protein sequence database in metastatic melanoma, searching for novel, relev...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310019253 | GPMDB
Resource Reanalysis 
ProteomicsA Protein Deep Sequencing Evaluation of Metastatic Melanoma Tissues, fractionated approach
Malignant melanoma has currently the highest increase of incidence of malignancies in the western world. In early stages, front line therapy is surgical excision of the primary tumor. Metastatic disease has previously has very limited possibilities to be cured. Recently, several protein kinase inhib...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-23 | MSV000080282 | MassIVE
UnknownClinical autism subscales have common genetic liabilities that are heritable, pleiotropic, and generalizable to the general population.
Not available
S-EPMC9192633 | biostudies-literature
UnknownSelection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations.
Not available
S-EPMC10275001 | biostudies-literature
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