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By taking advantage of the strong genetic interactions between trans-translation and other ribosome rescue systems, we have employed a transposon sequencing (Tn-Seq) to identify potential novel rescue factors in Bacillus subtilis. In addition to the identification the ArfA-type rescue factor BrfA, a...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2024-09-16 | PXD049370 | Pride
Bacterial toxin-antitoxin systems help bacteria to reduce their metabolism in various stressful conditions and also play a part in generating antibiotic tolerant bacterial subpopulation called persisters. Many toxins of the bacterial toxin-antitoxin systems are ribonucleases. Such toxins have been m...
ORGANISM(S): Escherichia coli K-12 
Data from ProteomeXchange, PXD ID: PXD001096. File: 130508_01_Orbi1_SK_SER_G150_T158_BOSS_2xenrich_repl1_try.mzml. Published as part of Proteomics. 2015 Jan 20 . From the Abstract: {{i}} A significant proportion of mammalian fertilization is mediated through the proteomic composition of the sperm s...
ORGANISM(S): Cow 
Macrolides are clinically important antibiotics thought to inhibit bacterial growth by impeding the passage of newly synthesized polypeptides through the nascent peptide exit tunnel of the bacterial ribosome. Recent data challenged this view by showing that macrolide antibiotics can differentially a...
ORGANISM(S): Escherichia coli BW25113 
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