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GenomicsSingle-cell sequencing of Klinefelter testicular biopsies
Single-cell sequencing of Klinefelter testicular biopsies
PRJNA534098 | ENA
TranscriptomicsTranscription profiling of testis biopsies to investigate testis developmental gene expression in cryptorchid boys at risk of azoospermia
Despite timely and successful surgery, 32% of patients with bilateral and 10% with unilateral cryptorchidism will develop azoospermia. Cryptorchid boys at risk of azoospermia display a typical testicular histology of impaired mini-puberty at the time of the orchidopexy. During mini-puberty increased...
ORGANISM(S): Homo sapiens 
2010-11-23 | E-GEOD-25518 | biostudies-arrayexpress
ProteomicsHuman testicular biopsies iTRAQ proteomics
We collected testes biopsies from NOA (severe spermatogenic defects, no spermatids or sperm) and OA (normal spermatogenesis, tubular lumen obstruction) patients for iTRAQ proteomics analyses, to screen the genes for which the altered expression is involved in spermatogenic defects
ORGANISM(S): Homo sapiens (Human) 
2025-06-11 | PXD060811 | Pride
Human Noa Itraq Testicular biopsies 
TranscriptomicsTranscriptional profiling of testicular biopsies with Sertoli-cell-only and spermatogonial presence
The aim of the study was to identify in vivo spermatogonial gene expression within the context of their biological niche. Identification of spermatogonial genes was done by t-testing on the replicates of Score 3 (Spermatogonia) and Score 2 (SCO) testicular biopsies. 3 biological replicates with sper...
ORGANISM(S): Homo sapiens 
2009-11-12 | E-GEOD-18997 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis
Identification of gene expression patterns that correlate with distinct stages of male germ cell development using biopsies from men with highly defined and homogenous testicular pathologies based on the Johnsen score procedure. The Johnsen score procedure is a classical histopathological scoring pr...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-TABM-234 | biostudies-arrayexpress
UnknownDetection of chlamydia infection within human testicular biopsies.
Not available
S-EPMC6810529 | biostudies-literature
TranscriptomicsAn expression atlas of human postnatal testicular cell development
Postnatal human male gonad development and function are known to involve many genes and pathways but our understanding of genome-wide developmental stage-specific and cell type-specific gene expression is far from complete. Integration of testicular and somatic data could elucidate regulatory mechan...
ORGANISM(S): Homo sapiens 
2012-10-28 | E-TABM-1214 | biostudies-arrayexpress
UnknownAltered microRNA profiles of testicular biopsies from patients with nonobstructive azoospermia.
Not available
S-EPMC6958976 | biostudies-literature
TranscriptomicsTranscription profiling of human seminiferous tubules from subfertile/infertile patients undergoing testicular sperm extraction as part of their treatment
43 biopsies were obtained from subfertile/infertile patients undergoing testicular sperm extraction (TESE) as part of their treatment. Labelled cDNAs were compared to a reference normal testis RNA (Ambion).
ORGANISM(S): Homo sapiens 
2007-03-15 | E-MEXP-1019 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of testicular biopsies with Sertoli-cell-only and spermatogonial presence
The aim of the study was to identify in vivo spermatogonial gene expression within the context of their biological niche. Identification of spermatogonial genes was done by t-testing on the replicates of Score 3 (Spermatogonia) and Score 2 (SCO) testicular biopsies.
ORGANISM(S): Homo sapiens 
2009-11-13 | GSE18997 | GEO
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