Sort   by:  
 Page size 
ProteomicsCCT3 acts as upstream of YAP and TFCP2 to be a potential target and tumor biomarker in liver cancer
Recently, we've reported that pro-tumorigenic roles of YAP in liver cancer are indispensable of TFCP2 act as upstream to simultaneously control YAP.The aim of this study is to uncover such proteins and evaluate whether the candidates are potential YAP-associated therapeutic target and diagnostic mar...
ORGANISM(S): Homo sapiens (Human) 
2019-09-11 | PXD013143 | Pride
Liver Human 
ProteomicsMulti-Omic and Functional Analysis for Classification and Treatment of Sarcomas with FUS-TFCP2 or EWSR1-TFCP2 Fusions
Linking clinical multi-omics analyses with mechanistic studies may improve the understanding of rare cancers. We leveraged two precision oncology programs to investigate rhabdomyosarcoma with FUS/EWSR1-TFCP2 fusions, an orphan malignancy without effective therapies. All tumors exhibited outlier ALK ...
ORGANISM(S): Homo sapiens (Human) 
2023-11-13 | PXD045522 | Pride
Alk Fus-tfcp2 Sarcoma Ewsr1-tfcp2 
GenomicsMulti-Omic and Functional Analysis for Classification and Treatment of Sarcomas with FUS-TFCP2 or EWSR1-TFCP2 Fusions
Multi-Omic and Functional Analysis for Classification and Treatment of Sarcomas with FUS-TFCP2 or EWSR1-TFCP2 Fusions
PRJNA930020 | ENA
GenomicsGenomic, transcriptomic, functional, and mechanistic characterization of rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusions (ACT-Seq)
Genomic, transcriptomic, functional, and mechanistic characterization of rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusions (ACT-Seq)
PRJNA930023 | ENA
GenomicsGenomic, transcriptomic, functional, and mechanistic characterization of rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusions (RNA-Seq)
Genomic, transcriptomic, functional, and mechanistic characterization of rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusions (RNA-Seq)
PRJNA930022 | ENA
GenomicsTFCP2 is a transcriptional regulator of heparan sulfate assembly and melanoma cell growth
TFCP2 is a transcriptional regulator of heparan sulfate assembly and melanoma cell growth
PRJNA931938 | ENA
UnknownMulti-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions.
Not available
S-EPMC10761971 | biostudies-literature
GenomicsGenome-wide analysis of YAP and TFCP2 binding DNA in liver cancer cells
To seek additional evidence that YAP closely interacts with TFCP2, we performed ChIP-seq assays in Bel-7402 cells using anti-TFCP2 or anti-YAP antibodies. We found that a subset of YAP binding regions overlapped with the TFCP2-occupied sites, suggesting that YAP- and TFCP2-regulated transcriptional ...
ORGANISM(S): Homo sapiens 
2017-09-22 | GSE99314 | GEO
TranscriptomicsMulti-Omic and Functional Analysis for Classification and Treatment of Sarcomas with FUS-TFCP2 or EWSR1-TFCP2 Fusions
Linking clinical multi-omics analyses with mechanistic studies may improve the understanding of rare cancers. We leverage two precision oncology programs to investigate rhabdomyosarcoma with FUS/EWSR1-TFCP2 fusions, an orphan malignancy without effective therapies. All tumors exhibit outlier ALK exp...
ORGANISM(S): Homo sapiens 
2023-11-06 | GSE224183 | GEO
TranscriptomicsGenome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells
To identify YAP and TFCP2 co-regulated genes, RNA-seq was also performed in Bel-7402 cells before and after knocking down YAP or TFCP2. From the RNA-seq data, 2165 genes were found that were possibly co-regulated by YAP and TFCP2.
ORGANISM(S): Homo sapiens 
2017-09-22 | GSE99313 | GEO
Sort   by:  
 Page size