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ProteomicsMS-based quantitative proteomic analysis of total proteomes from T. gondii strains upon MORC’s depletion and TgHDAC3 inhibition.
T. gondii has a complex life cycle typified by an asexual development taking place in vertebrate, and a sexual reproduction which occurs exclusively in felids and thereby is less studied. The developmental transitions rely on changes in gene expression patterns, and recent studies have assigned role...
ORGANISM(S): Toxoplasma gondii 
2020-01-09 | PXD016845 | Pride
Toxoplasma gondii Tghdac3 Tgme49_305340 Nanolc-ms/ms 
TranscriptomicsDrug-inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites
Plasmodium and Toxoplasma are parasites of major medical importance that belong to the Apicomplexa phylum of protozoa. These parasites transform into various stages during their life cycle and express a specific set of proteins at each stage. Although still little is known of how gene expression is ...
ORGANISM(S): Toxoplasma gondii 
2010-06-21 | E-GEOD-15241 | biostudies-arrayexpress
GenomicsGenome-wide Occupancy Changes of TgHDAC3 Before and After Deletion of Transcription Factor AP2XII-5
Genome-wide Occupancy Changes of TgHDAC3 Before and After Deletion of Transcription Factor AP2XII-5
PRJNA1188100 | ENA
GenomicsDrug-inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites
Plasmodium and Toxoplasma are parasites of major medical importance that belong to the Apicomplexa phylum of protozoa. These parasites transform into various stages during their life cycle and express a specific set of proteins at each stage. Although still little is known of how gene expression is ...
ORGANISM(S): Toxoplasma gondii ME49 Toxoplasma gondii 
2009-03-19 | GSE15241 | GEO
GenomicsGenome-wide Occupancy Changes of TgHDAC3 Before and After Deletion of Transcription Factor AP2XII-5
Toxoplasma gondii is a ubiquitous protozoan parasite with a complex life cycle containing multiple developmental stages. The parasites have distinct gene expression patterns at different stages to enable stage specific life activities, but the underlying regulatory mechanisms are largely unknown. In...
ORGANISM(S): Toxoplasma gondii 
2025-11-30 | GSE282299 | GEO
UnknownTheileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion.
Not available
S-EPMC9325746 | biostudies-literature
GenomicsToxoplasma gondii
Drug-inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites
PRJNA116441 | ENA
GenomicsTheileria annulata TaHDAC1
Theileria annulata histone deacetylase 1 (TaHDAC1) regulates schizont to merozoite stage conversion
PRJEB50801 | ENA
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