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ProteomicsThe formation of the 'footprint of death' as a mechanism for generating large substrate-bound extracellular vesicles that mark the site of cell death
Apoptotic cells communicate to phagocytic cells through releasing soluble factors and apoptotic cell derived extracellular vesicles. However, whether there are additional factors that remain attached at the site of cell death to signal to phagocytic cells is currently unknown. Here we show that apop...
ORGANISM(S): Homo sapiens (Human) 
2025-10-15 | PXD067718 | Pride
Ev Extracellular vesicle The footprint of death F-apoev Food 
UnknownThe formation of the 'footprint of death' as a mechanism for generating large substrate-bound extracellular vesicles that mark the site of cell death.
Not available
S-EPMC12528690 | biostudies-literature
UnknownCOVID-19 clinical footprint to infer about mortality.
Not available
S-EPMC9877559 | biostudies-literature
GenomicsCell-free DNA comprises an in vivo, genome-wide nucleosome footprint that informs its tissue(s)-of-origin
Nucleosomes are the basic unit of packaging of eukaryotic chromatin, and nucleosome positioning can differ substantially between cell types. Here, we sequence 14.5 billion plasma-borne cell-free DNA (cfDNA) fragments (700-fold coverage) to generate genome-wide maps of in vivo nucleosome occupancy. W...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-71378 | biostudies-arrayexpress
MetabolomicsComparative analysis of the adaptation of Staphylococcus aureus to internalization by different types of human non-professional phagocytic host cells (NMR assay)
Staphylococcus aureus is a human pathogen that can cause a wide range of diseases. Although formerly regarded as extracellular pathogen, it has been shown that S. aureus can also be internalized by host cells and persist within these cells. In the present study, we comparatively analyzed survival an...
2015-07-01 | MTBLS102 | MetaboLights
UnknownThe carbon footprint and energy consumption of liver transplantation.
Not available
S-EPMC11743657 | biostudies-literature
UnknownThe metabolic footprint of the airway bacterial community in cystic fibrosis.
Not available
S-EPMC5493850 | biostudies-literature
TranscriptomicsGlobal response to chemotherapy-induced apoptosis
Here we use an integrated systems-level examination of transcription, translation, and proteolysis to explore how cancer cells struggle with a chemotherapeutic drug prior to succumbing to apoptosis. As a model system we study myeloma cells exposed to the proteasome inhibitor bortezomib, a first-line...
ORGANISM(S): Homo sapiens 
2013-10-17 | E-GEOD-48785 | biostudies-arrayexpress
Transcriptomicsbrain expression data from adult mice prenatally exposed to ethanol
Moderate alcohol consumption during pregnancy can result in a heterogeneous range of neurobehavioural and cognitive effects, termed fetal alcohol spectrum disorders (FASD). We have developed a mouse moder of FASD that involves moderate ethanol exposure throughout gestation achieved by voluntary mat...
ORGANISM(S): Mus musculus 
2011-12-10 | E-GEOD-34305 | biostudies-arrayexpress
UnknownA low-footprint, fluorescence-based bacterial time-kill assay for estimating dose-dependent cell death dynamics.
Not available
S-EPMC10983867 | biostudies-literature
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