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TranscriptomicsSexually dimorphic gene expression in the hypothalamus, pituitary gland and cortex by SAGE
C57BL6 mice (12-15 weeks old) were obtained from Charles River Laboratories (St. Constant, Québec). They were housed in an air-conditioned room (19-25Åé) with controlled lighting from 07:15 to 19:15 h and were given free access to laboratory chow (Lab Rodent Diet No. 5002, Ren’s Feed and Suppliers, ...
ORGANISM(S): Mus musculus 
2006-01-13 | E-GEOD-2156 | biostudies-arrayexpress
TranscriptomicsTestosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice
Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin (KISS1) do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in the hypothalamus have yet to be explored by genome-wide methods. Using micro-disse...
ORGANISM(S): Mus musculus 
2011-08-21 | E-GEOD-28383 | biostudies-arrayexpress
ProteomicsBovine hypothalamic LC-MS/MS
The objective of the current study is to identifiy abundant proteins in the hypothalamus between pre- and post-pubertal Brahman heifers using LC-ESI-MS/MS
ORGANISM(S): Bos indicus 
2022-08-11 | PXD009620 | Pride
Brahman Puberty Heifer The hypothalamus Bos indicus 
ProteomicsGoose,hypothalamus,LC-MS/MS
Comparative proteomic analysis of hypothalamus tissue from Huoyan geese between pre-laying period and laying period using an iTRAQ-based approach
ORGANISM(S): Anser cygnoides 
2022-03-06 | PXD006842 | Pride
Lc-ms/ms Goose Hypothalamus 
ProteomicsAcetylome analyses provide new insights into the effect of chronic intermittent hypoxia on hypothalamus-dependent endocrine metabolism impairment
Background: Paediatric obstructive sleep apnoea (OSA) is a highly prevalent sleep disorder resulting in chronic intermittent hypoxia (CIH) that has been linked to metabolism and endocrine impairment. Protein acetylation, which is a frequently occurring posttranslational modification, plays pivotal r...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD051767 | Pride
Lysine acetylation Paediatric obstructive sleep apnoea (osa). Endocrine metabolism Chronic intermittent hypoxia Hypothalamus 
TranscriptomicsSexually Dimorphic Gene Expression in the Adult Mouse Hypothalamus and Bed Nucleus of the Stria Terminalis
To identify genes that are downstream of gonadal hormones and that control dimorphic behaviors, we used a MEEBO array platform to profile gene expression of adult male and female hypothalamus against a whole brain reference sample. The experimental design allowed us to identify genes that are upregu...
ORGANISM(S): Mus musculus 
2011-10-28 | E-GEOD-33307 | biostudies-arrayexpress
TranscriptomicsAnalysis of Genes in the Hypothalamus Controlling Feed Intake and Energy Metabolism in Neonatal Chicks
Delayed access to feed following hatching has been associated with reduction in growth performance in chicks. However, the gene networks within the hypothalamus that regulate feed intake and metabolism, and the effects of fasting on those pathways are not well understood. The present experiment eval...
ORGANISM(S): Gallus gallus 
2008-10-18 | E-GEOD-13257 | biostudies-arrayexpress
TranscriptomicsEffects of pulp and paper mill effluents on gene expression in the fathead minnow hypothalamus
We evaluated the possible mechanisms by which exposures to pulp and paper mill effluents gene expression in the fathead minnow hypothalamus Keywords: Toxicology Sexually mature fathead minnows were exposed to 100% pulp and paper mill effluents for 5 days. Tanks contained 4 females and 2 males. A ...
ORGANISM(S): Pimephales promelas 
2010-07-07 | E-GEOD-17130 | biostudies-arrayexpress
TranscriptomicsEffect of short- and long-term morphine treatment on gene expression in the hypothalamus and pituitary
Addictive drugs including opioids activate signal transduction pathways that regulate gene expression in the brain. However, changes in CNS gene expression following morphine exposure are poorly understood. We studied the effect of short- and long-term morphine treatment on gene expression in the hy...
ORGANISM(S): Mus musculus 
2008-09-30 | E-GEOD-9525 | biostudies-arrayexpress
TranscriptomicsGene expression in liver, gill, hypothalamus, pituitary, and olfactory rosettes from Atlantic salmon parr and smolt
To identify genes involved in the developmental process of Atlantic salmon smoltification, gene expression was compared between smolt and parr in tissues involved in osmoregulation (gill), metabolism (liver), imprinting (olfactory rosettes) and neuroendocrine control (hypothalamus and pituitary). ...
ORGANISM(S): Salmo salar 
2012-08-20 | E-GEOD-33711 | biostudies-arrayexpress
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