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GenomicsMLL1 is essential for the senescence-associated secretory phenotype [ChIP-Seq]
Oncogene-induced senescence (OIS) and therapy-induced senescence (TIS), while tumor-suppressive, also promote procarcinogenic effects by activating the DNA damage response (DDR), which in turn induces inflammation. This inflammatory response prominently includes an array of cytokines known as the se...
ORGANISM(S): Homo sapiens 
2016-02-23 | E-GEOD-78141 | biostudies-arrayexpress
GenomicsMLL1 is essential for the senescence-associated secretory phenotype
This SuperSeries is composed of the SubSeries listed below. Oncogene-induced senescence (OIS) and therapy-induced senescence (TIS), while tumor-suppressive, also promote procarcinogenic effects by activating the DNA damage response (DDR), which in turn induces inflammation. This inflammatory respon...
ORGANISM(S): Homo sapiens 
2016-02-22 | E-GEOD-78142 | biostudies-arrayexpress
TranscriptomicsMLL1 is essential for the senescence-associated secretory phenotype [RNA-Seq]
Oncogene-induced senescence (OIS) and therapy-induced senescence (TIS), while tumor-suppressive, also promote procarcinogenic effects by activating the DNA damage response (DDR), which in turn induces inflammation. This inflammatory response prominently includes an array of cytokines known as the se...
ORGANISM(S): Homo sapiens 
2016-02-23 | E-GEOD-78138 | biostudies-arrayexpress
ProteomicsSenescence 1
Bag3 and MVP regulate apoptosis resistance in Therapy Induced Senescence (TIS)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079929 | MassIVE
ProteomicsSenescence 3
Bag3 and MVP regulate apoptosis resistance in Therapy Induced Senescence (TIS)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079924 | MassIVE
ProteomicsSenescence 6
Bag3 and MVP regulate apoptosis resistance in Therapy Induced Senescence (TIS)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079989 | MassIVE
ProteomicsSenescence 5
Bag3 and MVP regulate apoptosis resistance in Therapy Induced Senescence (TIS)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079931 | MassIVE
ProteomicsSenescence 2
Bag3 and MVP regulate apoptosis resistance in Therapy Induced Senescence (TIS)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079932 | MassIVE
ProteomicsSenescence 4
Bag3 and MVP regulate apoptosis resistance in Therapy Induced Senescence (TIS)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079930 | MassIVE
ProteomicsImmunopeptidomics of Acute Myeloid Leukemia (AML) Blast cells after Therapy-Induced Senescence (TIS) with Cytarabine.
Resistance or relapse upon chemotherapy are major determinants of treatment failure in acute myeloid leukemia (AML). Therapy-induced senescence (TIS) is a potential outcome of chemotherapy, but its immunological consequences in AML remain unclear. We show that ex-vivo chemotherapy induces senescence...
ORGANISM(S): Homo sapiens (Human) 
2026-08-13 | PXD068731 | Pride
Immunopeptidomics Therapy-induced senescence Tis Hla Ligandome Mhc Cytarabine Ligandomics Immunopeptidome Timstof scp Acute myeloid leukemia Aml 
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