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UnknownDeep Proteomic Compound Profiling with the Orbitrap Ascend Tribrid Mass Spectrometer Using Tandem Mass Tags and Real-Time Search.
Not available
S-EPMC10785648 | biostudies-literature
UnknownEvaluation of the Orbitrap Ascend Tribrid Mass Spectrometer for Shotgun Proteomics.
Not available
S-EPMC10528367 | biostudies-literature
UnknownApplying UHPLC-HRAM MS/MS Method to Assess Host Cell Protein Clearance during the Purification Process Development of Therapeutic mAbs.
Not available
S-EPMC11396427 | biostudies-literature
UnknownTop-down mass spectrometry analysis of capsid proteins of recombinant adeno-associated virus using multiple ion activations and proton transfer charge reduction.
Not available
S-EPMC11880350 | biostudies-literature
ProteomicsCatechol-O-Methyltransferase connects dopamine homeostasis to redox signaling, metal homeostasis and protein folding in schizophrenia
Dysregulation of dopamine (DA) signaling and redox homeostasis contributes to multiple neuropsychiatric and neurodegenerative disorders. Polymorphisms that influence the activity of catechol‑O‑methyltransferase (COMT), an enzyme critical for degrading dopamine (DA) in the dorsolateral prefrontal cor...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-09-28 | PXD075030 | Pride
Limited proteolysis Thermo-fisher ascend Rat Pc12 cells 
ProteomicsProteogenomic analysis of hiPSC cultures from a healthy donor
Proteogenomic analysis of three stem cell samples from a healthy donor. The cell lines used here are commercially available as induced pluripotent stem cells (iPSC) via retroviral reprogramming of skin fibroblasts isolated from the PGP1 donor from the Personal Genome Project (PGP) (Coriell, GM23338)...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-07-03 | MSV000095226 | MassIVE
UnknownImplementation of Infrared-Activated Negative Electron Transfer Dissociation (IR-NETD) Using Xenon on a Quadrupole-Orbitrap-Quadrupole Linear Ion Trap Mass Spectrometer.
Not available
S-EPMC12784409 | biostudies-literature
ProteomicsExtensive backbone cleavage coverage of intact proteoforms in a mass range of 10-70 kDa by integrating electron, collision, and photon-based fragmentation techniques during an electrophoretic timescale
Capillary zone electrophoresis (CZE) –-tandem mass spectrometry (MS/MS) has been documented as a useful tool for top-down proteomics (TDP). However, CZE-MS/MS-based TDP typically has limited backbone cleavage coverage for identified proteoforms due to the use of traditional collision-based fragmenta...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD070486 | Pride
Capillary zone electrophoresis mass spectrometry  top-down proteomics  orbitrap ascend tribrid  ultraviolet photodissociation  higher-energy collisional dissociation  electron transfer dissociation 
ProteomicsPhosphoproteomics evaluation of the effect of GLP-1 on the porcine pacemaker
GLP-1 induces an increase in heart rate, but its mechanism remains elusive. We used a phosphoproteomic approach to evaluate the effect of GLP-1 on the porcine sinus node. Tissue samples from the sinus node region and left ventricle were collected from eight animals following a 60-minute infusion wit...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-06-10 | PXD042583 | Pride
Heart Phosphoproteomics Pig Pacemaker Glucagon-like peptide 1 Porcine Glp-1 Sinus node 
ProteomicsAAV2 induced RPA exhaustion generates cellular DNA damage and restricts viral gene expression
In Gel Digestion Each lane sample was then cut into small rectangular pieces and divided into two fractions: fraction 2 containing the streptavidin band and fraction 1 containing the remaining proteins. For in gel digestion, both fractions were subjected to several rounds of washing to remove salts ...
ORGANISM(S): Adeno-associated Virus 2 Srivastava/1982 (ncbitaxon:648242) Homo Sapiens (ncbitaxon:9606) 
2025-06-18 | MSV000098258 | MassIVE
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