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ModelsBravo2012 - Modelling blood coagulation factor Va inactivation by APC
Mathematical model of blood coagulation factor Va and Va fragment inactivation by APC, reactions with Xa and prothrombinase-prothrombin complex formation.
2024-09-02 | BIOMD0000000739 | BioModels
TranscriptomicsThe transient inactivation of the master cell cycle phosphatase Cdc14 causes genomic instability in diploid cells of Saccharomyces cerevisiae.
Genomic instability is a common feature found in cancer cells. Accordingly, many tumor suppressor genes identified in familiar cancer syndromes are involved in the maintenance of the stability of the genome during every cell division, and are commonly referred to as caretakers. Inactivating mutation...
ORGANISM(S): Saccharomyces cerevisiae 
2015-05-05 | E-GEOD-68530 | biostudies-arrayexpress
MetabolomicsMultiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
Membrane lipids and their metabolism have key functions in neurotransmission. Here we provide a quantitative lipid inventory of mouse and rat synaptic junctions. To this end, we developed a multiomics extraction and analysis workflow to probe the interplay of proteins and lipids in synaptic signal t...
2021-09-27 | MTBLS1531 | MetaboLights
UnknownMulti-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.
Not available
S-EPMC4872014 | biostudies-literature
UnknownConserved Noncoding Cis-Elements Associated with Hibernation Modulate Metabolic and Behavioral Adaptations in Mice.
Not available
S-EPMC11230392 | biostudies-literature
ProteomicsOn-chip AP-MS: Interaction proteomics on a microfluidics platform
Here we present a microfluidics-based affinity purification-mass spectrometry (AP-MS) pipeline to identify protein-protein interactions (PPI) using minute amounts of input material. The use of this automated platform allowed us to identify the human cohesin and CCC complex from only 4 micrograms of ...
ORGANISM(S): Homo sapiens (Human) 
2022-03-10 | PXD011323 | Pride
Interaction proteomics Low input Ap-ms 
ProteomicsOn-chip AP-MS: Interaction proteomics on a microfluidics platform
Essentially all cellular processes are orchestrated by protein-protein interactions (PPIs). In recent years, affinity purification coupled to mass spectrometry (AP-MS) has been the preferred method to identify cellular PPIs. Here we present a microfluidics-based (AP-MS) workflow to identify PPIs usi...
ORGANISM(S): Homo sapiens (Human) 
2019-04-02 | PXD012800 | Pride
Interaction proteomics Low input Ap-ms 
UnknownImmune-mediated diarrhea and colitis with normal biochemical, endoscopic and histologic findings: a retrospective study.
Not available
S-EPMC12850695 | biostudies-literature
ProteomicsDevelopment and qualification of a dendritic cell internalization assay contributing to the immunogenicity risk evaluation of biotherapeutics
The appended raw files, csv files and other documents were deposited into the public domain in support for the publication "Development and characterization of a dendritic cell internalization assay contributing to the immunogenicity risk evaluation of biotherapeutics" by Michel Siegel, Aman Padamse...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-12 | MSV000095578 | MassIVE
TranscriptomicsTranscriptional profiling of mouse SCNT and ICSI eight-cell embryos with different developmental timings
To gain insight if developmental timings of early embryonic cleavages relate to systematic gene expression differences
ORGANISM(S): Mus musculus 
2011-10-31 | E-TABM-1182 | biostudies-arrayexpress
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