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MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
Other,MultiomicsChevrette et al 2019 Insect-associated Streptomyces
Paper title: The antimicrobial potential of Streptomyces from insect microbiomes. Author list: Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo ...
ORGANISM(S): Pseudonocardia Kitasatospora Streptomyces Gordonia <actinomycete> 
2019-12-18 | MSV000084723 | MassIVE
UnknownIs spirituality a component of wisdom? Study of 1,786 adults using expanded San Diego Wisdom Scale (Jeste-Thomas Wisdom Index).
Not available
S-EPMC7736537 | biostudies-literature
Genomicsmetagenome
human gut and groundwater harbor non-photosynthetic bacteria
PRJNA321218 | ENA
Metabolomics,MultiomicsGNPS - Chevrette et al 2019 Insect-associated Streptomyces
Paper title: The antimicrobial potential of Streptomyces from insect microbiomes. Author list: Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo ...
ORGANISM(S): Kitasatospora (ncbitaxon:2063) Gordonia <actinomycete> (ncbitaxon:2053) Pseudonocardia (ncbitaxon:1847) Streptomyces (ncbitaxon:1883) 
2019-12-18 | MSV000084723 | GNPS
TranscriptomicsRNA-seq transcriptome profiling of the psychrophilic diatom Fragilariopsis cylindrus grown at 0 degree Celsius and two levels of salinity
The data set described here complements data available under accession number E-MTAB-5153. We performed bulk RNA-sequencing experiments to examine gene expression in the genome of the cold-adapted (psychrophilic) marine diatom Fragilariopsis cylindrus growing at 0 degree Celsius and salinity of 34 ...
ORGANISM(S): Fragilariopsis cylindrus 
2022-04-30 | E-MTAB-8665 | biostudies-arrayexpress
TranscriptomicsTranscriptomic definition of curcumin treated microglia
Curcumin is a potent modulator of the inflammatory transcriptome in microglia We have performed global gene expression analysis of BV-2 microglial cells under the following conditions: untreated, 20 µM Curcumin-treated, 100ng/ml LPS-treated, or 20 µM Curcumin-treated + 100ng/ml LPS-treated
ORGANISM(S): Mus musculus 
2010-09-29 | E-GEOD-23639 | biostudies-arrayexpress
UnknownAssociation of Aβ deposition and regional synaptic density in early Alzheimer's disease: a PET imaging study with [11C]UCB-J.
Not available
S-EPMC7786921 | biostudies-literature
UnknownThe impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study.
Not available
S-EPMC7417808 | biostudies-literature
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