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UnknownMechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses.
Not available
S-EPMC6695567 | biostudies-literature
UnknownCompound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment.
Not available
S-EPMC5556032 | biostudies-literature
UnknownGlucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor.
Not available
S-EPMC5567040 | biostudies-literature
UnknownSelective Modulation of the Human Glucocorticoid Receptor Compromises GR Chromatin Occupancy and Recruitment of p300/CBP and the Mediator Complex.
Not available
S-EPMC10957501 | biostudies-literature
UnknownCrosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells.
Not available
S-EPMC10425521 | biostudies-literature
UnknownCo-Activation of Glucocorticoid Receptor and Peroxisome Proliferator-Activated Receptor-γ in Murine Skin Prevents Worsening of Atopic March.
Not available
S-EPMC7611015 | biostudies-literature
UnknownPlasmodium berghei NK65 in Combination with IFN-γ Induces Endothelial Glucocorticoid Resistance via Sustained Activation of p38 and JNK.
Not available
S-EPMC5625030 | biostudies-literature
UnknownCrosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression.
Not available
S-EPMC11059514 | biostudies-literature
ProteomicsThe auophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages
Glucocorticoids are widely used to treat inflammatory disorders; however, prolonged use of glucocorticoids results in side effects including osteoporosis, diabetes and obesity. Compound A (CpdA), identified as a selective NR3C1/glucocorticoid receptor (nuclear receptor subfamily 3, group C, member 1...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-11 | PXD012121 | Pride
Autophagy  autophagy receptors  cpda  glucocorticoids  inflammation  nfe2l2/nrf2  sqstm1/p62 
ProteomicsOptimizing efficacy to safety ratio of glucocorticoids in rheumatoid arthritis models by leveraging PPARα agonism
Glucocorticoids remain essential therapies for immune- and inflammatory diseases such as rheumatoid arthritis (RA) but are notorious for their metabolic side effects. Given the anti-inflammatory and metabolically favorable actions of peroxisome-proliferator activated nuclear receptor (PPAR) agonists...
ORGANISM(S): Homo sapiens (Human) 
2026-09-17 | PXD084343 | Pride
Human Gw7647 Ppar Dexamethasone Glucocorticoid hormones Fibroblast-like synoviocytes 
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