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TranscriptomicsTranscription profiling of S. typhimurium during the intracellular growth phase of infection pathogenesis following infection of macrophages
DNA microarrays were used to provide a global transcriptional profile of S. typhimurium during the intracellular growth phase of infection pathogenesis following infection of macrophages.
ORGANISM(S): Salmonella enterica serovar Typhimurium 
2005-08-30 | E-MEXP-415 | biostudies-arrayexpress
ProteomicsHypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity
The long-term impact of systemic hypoxia resulting from Acute Respiratory Distress Syndrome (ARDS) on the function of short-lived innate immune cells is unclear. We show that patients 3-6 months after recovering from ARDS have persistently impaired circulating neutrophil effector functions and an in...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD065461 | Pride
Epigenetics Neutrophil Hypoxia Reprogramming 
ProteomicsHypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity
The long-term impact of systemic hypoxia resulting from Acute Respiratory Distress Syndrome (ARDS) on the function of short-lived innate immune cells is unclear. We show that patients 3-6 months after recovering from ARDS have persistently impaired circulating neutrophil effector functions and an in...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD065519 | Pride
Epigenetics Neutrophil Hypoxia Reprogramming 
TranscriptomicsTranscription profiling of human CD14+ monocytes treated with innate defence regulator peptide IDR-1 in the presence/absence of lipopolyssacharide
Effect of peptide IDR-1 on CD14+ human monocytes. >br< >br< Effect of peptide IDR-1 on LPS-induced responses in CD14+ human monocytes.>br< >br< Human peripheral blood mononuclear cells (PBMC) were treated with innate defence regulator peptide IDR-1 in the presence and absence of LPS (purified from P...
ORGANISM(S): Homo sapiens 
2007-04-10 | E-FPMI-8 | biostudies-arrayexpress
TranscriptomicsPromoter H3K4 methylation reveals the dynamic reinforcement of activation-induced pathways in human CD4 T cells with differential kinetics in naïve and memory cells (RNA-Seq)
The epigenetic determinants driving the rapid responses of memory CD4 T cells to antigen are currently an area of active research. While much has been done to characterize various Th subsets and their associated genome-wide epigenetic patterns, the dynamics of histone modifications during CD4 T cel...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-73213 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica Typhimurium during infection of human epithelial cells
Epithelial cells are the first cell type Salmonella Typhimurium will encounter when infecting a host. Using DNA array techology we identified the Salmonella enterica Typhimurium genes regulated inside human epithelial cells and their variation through time.
ORGANISM(S): Salmonella typhimurium 
2009-04-08 | E-MEXP-1368 | biostudies-arrayexpress
MetabolomicsMetabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

BACKGROUND: One-third of inflammatory bowel disease (IBD) patients show no response to infliximab (IFX) induction therapy, and approximately half of patients responding become unresponsive over time. Thus, identification of potential treatment response biomarkers are of great cl...

2022-01-13 | MTBLS239 | MetaboLights
UnknownHypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity.
Not available
S-EPMC12571872 | biostudies-literature
UnknownRich club analysis in the Alzheimer's disease connectome reveals a relatively undisturbed structural core network.
Not available
S-EPMC4504816 | biostudies-literature
UnknownPredicting Antidepressant Treatment Response From Cortical Structure on MRI: A Mega-Analysis From the ENIGMA-MDD Working Group.
Not available
S-EPMC11702469 | biostudies-literature
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