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TranscriptomicsNext Generation Sequencing Identifies Differentially Expressed Genes in Zebrafish Embryos and Larvae Following Benzo[a]pyrene Exposure
Purpose: This study aimed to identify differentially expressed genes and transcripts in zebrafish embryos and larvae following benzo[a]pyrene (BaP) exposure. Methods: Adult zebrafish (2 males × 4 females, N=6 replicate tanks for each treatment) were acclimated for 7 days in an 818 Low Temp Illuminat...
ORGANISM(S): Danio rerio 
2015-09-04 | E-GEOD-64198 | biostudies-arrayexpress
UnknownResidual lung abnormality following COVID-19 hospitalisation is characterised by biomarkers of epithelial injury.
Not available
S-EPMC12860639 | biostudies-literature
ProteomicsBumblebee venom - The genomes of two key bumblebee species with primitive eusocial organization
This experiment provide a comprehensive overview of proteins present in bumblebee venom.
ORGANISM(S): Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris) 
2015-04-29 | PXD001623 | Pride
Venom Toxing Bumblebee 
TranscriptomicsExpression analysis in brain endothelial cells of Gαq/11beKO mice to elucidate CO2-induced vasoreactivity mechanism
CO2-induced vasoreactivity is an important mechanism to remove CO2 from the brain. Our previous work has shown that in brain endothelial cells Gαq and Gα11, that can replace each other and induce a common intracellular pathway, are required for normal vascular reactivity to CO2 stimulation. Addition...
ORGANISM(S): Mus musculus 
2019-12-20 | E-MTAB-8521 | biostudies-arrayexpress
TranscriptomicsdFOXO targets in Drosophila melanogaster
dFOXO targets in adult Drosophila melanogaster females, and the effect of insulin signalling and stress on binding. The experimets determined the binding locations of dFOXO in the whole adult female fly using ChIP-chip. The protocol was validated using mock conditions: pre-immune serum or IP on chro...
ORGANISM(S): Drosophila melanogaster 
2011-06-18 | E-TABM-751 | biostudies-arrayexpress
TranscriptomicsThe little elongation complex (LEC) regulates small nuclear RNA transcription
The Eleven-nineteen Lysine-rich Leukemia (ELL)-containing Super Elongation Complex (SEC) containing P-TEFb is a key regulator in the expression of HOX genes in Mixed Lineage Leukemia (MLL)-based leukemia. We have identified an SEC-like complex in Drosophila, as well as a distinct ELL-containing comp...
ORGANISM(S): Drosophila melanogaster 
2011-12-22 | E-GEOD-32120 | biostudies-arrayexpress
TranscriptomicsIntestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity
We identified that Drosophila FoxA transcription Fork Head (FKH) function is necessary for reduced insulin signalling and rapamycin induced longevity. Furthermore, we determined that FKH function in the gut tissue alone is sufficient to extend lifespan. We carried out RNA-sequencing in gut tissue o...
ORGANISM(S): Drosophila melanogaster 
2017-09-23 | E-MTAB-6056 | biostudies-arrayexpress
GenomicsGemone-wide maps of PRC2 complex components and chromatin states in prostate cancer cell lines
We report the high-throughput profiling of PRC2 core subunits chromatin states and histone modifications in two prostate cancer cell lines, androgen-dependent cells LNCaP and androgen-independent cells LNCaP-abl (abl). By obtaining over 1 billion bases of sequence from chromatin immunoprecipitated D...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39459 | biostudies-arrayexpress
TranscriptomicsRapid clearance of PcG histone modifications from Hox genes anticipates motor neuron differentiation: ChIP-chip
[original Title] Rapid and synchronous clearance of PcG histone modifications from Hox genes anticipates motor neuron differentiation. Hox genes are expressed in patterns that are spatially and temporally collinear with their chromosomal organization. This feature is an evolutionarily conserved hall...
ORGANISM(S): Mus musculus 
2013-07-04 | E-GEOD-19447 | biostudies-arrayexpress
UnknownViral and Host Factors Are Associated With Mortality in Hospitalized Patients With COVID-19.
Not available
S-EPMC11175705 | biostudies-literature
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