Threshold-dependent

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Proteomics (2467)
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Organisms

Allexis (2427)
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Organisms

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Tissue

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Cell suspension culture (36)
Blood serum (35)
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Disease

Disease free (62)
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Prostate adenocarcinoma (8)
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Brain glioblastoma multiforme (7)
Cardiovascular system disease (7)
Chronic myeloid leukemia (7)
Bacterial infectious disease (5)
Glioblastoma (5)
Multiple myeloma (5)
Multiple sclerosis (5)
Neuroblastoma (5)
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Liver disease (1)
Polycythemia due to hypoxia (1)
Osteosarcoma (1)

Technology Type

Mass Spectrometry (2427)
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Bottom-up proteomics (386)
Affinity purification coupled with mass spectrometry proteomics (332)
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Gel-based experiment (162)
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All-ion fragmentation (13)
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DiaPASEF (9)
MSE (9)
RNA mass spectrometry (7)
Immunopeptidomics (6)
Mass spectrometry imaging (4)
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NMR spectroscopy (1)
Gel-based quantification method (1)
Gel-free quantification method (1)
Glycoproteomics (1)
HDMSE (1)
Proteogenomics (1)
Sodium dodecyl sulfate polyacrylamide gel electrophoresis (1)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (37)
Liquid Chromatography MS - negative - reverse phase (33)
Liquid Chromatography MS - positive - reverse-phase (15)
LTQ (12)
Liquid Chromatography MS - negative - reverse-phase (12)
Liquid Chromatography MS - alternating - reverse phase (8)
Liquid Chromatography MS - alternating - hilic (6)
Liquid Chromatography MS - negative - hilic (6)
Liquid Chromatography MS - negative (4)
Liquid Chromatography MS - positive (4)
Illumina HiSeq 2000 (3)
Q Exactive (3)
Orbitrap Fusion Lumos (3)
Liquid Chromatography MS - (3)
Liquid Chromatography MS - positive - hilic (3)
Illumina HiSeq 2500 (2)
SolariX (2)
LTQ Orbitrap (2)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (2)
Gas Chromatography MS - positive (2)
Illumina Hiseq 2000 (1)
Illumina NovaSeq X (1)
BGISEQ-500 (1)
Illumina NovaSeq 6000 (1)
Impact HD UHR-QqTOF-MS (1)
MS:1000031 (1)
Orbitrap Eclipse (1)
Orbitrap Fusion (1)
Q Exactive HF-X (1)
Thermo Exploris 480 (1)

Publication Date

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2020 (203)
2019 (175)
2018 (149)
2017 (107)
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2015 (53)
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2012 (10)
2008 (9)
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2004 (6)
2009 (4)
2006 (3)

UNIPROT ID/AC

P02340 (1)
Q08048 (1)
P46414 (1)
P23748 (1)
P32944 (1)
Q08471 (1)
Q10752 (1)
P31750 (1)
Q9NTU9 (1)
Q3T1B0 (1)
Q9NWT6 (1)
P16157 (1)
Q9Y2N7 (1)
Q99814 (1)
P42771 (1)
P11802 (1)
P01008 (1)
P10646 (1)
P12259 (1)
P00451 (1)
P00740 (1)
P00742 (1)
P08709 (1)
P13726 (1)
P08574 (1)
O96020 (1)
P46527 (1)
P24941 (1)
P00734 (1)
P24864 (1)

CHEBI ID

CHEBI:16335 (11)
CHEBI:16856 (9)
CHEBI:15741 (9)
CHEBI:6650 (9)
CHEBI:26271 (8)
CHEBI:17858 (8)
CHEBI:17533 (8)
CHEBI:15428 (8)
CHEBI:28044 (8)
CHEBI:16027 (8)
CHEBI:30915 (8)
CHEBI:15354 (8)
CHEBI:30769 (8)
CHEBI:17822 (7)
CHEBI:17202 (7)
CHEBI:22660 (7)
CHEBI:18186 (7)
CHEBI:16811 (7)
CHEBI:17562 (7)
CHEBI:17015 (7)
CHEBI:7916 (7)
CHEBI:15891 (7)
CHEBI:16449 (7)
CHEBI:29016 (7)
CHEBI:9574 (1)
CHEBI:16247 (1)
CHEBI:18059 (1)
CHEBI:50967 (1)
CHEBI:15379 (1)
CHEBI:16991 (1)

Metabolite Name

Pantothenic acid (17)
Taurine (17)
Adenosine (15)
Choline (14)
Azelaic acid (14)
Pyroglutamic acid (12)
Methionine (12)
4-Hydroxybenzaldehyde (12)
Cytosine (12)
L-Tryptophan (12)
Adenine (12)
Xanthine (12)
Guanosine (12)
Uridine (12)
Creatinine (12)
Creatine (12)
L-Tyrosine (12)
L-Alanine (11)
Uracil (11)
L-Glutamic acid (11)
Arginine (11)
Malic acid (11)
Guanine (11)
Glutamine (11)
L-Serine (11)
L-Phenylalanine (11)
1-Aminocyclopropane-1-carboxylic acid (10)
L-Lysine (10)
Ornithine (10)
Carnitine (10)

First Public Date

2014 (32)
2026 (27)
2024 (19)
2021 (16)
2025 (12)
2023 (11)
2017 (10)
2020 (8)
2019 (8)
2016 (8)
2018 (6)
2022 (5)
2015 (5)
2013 (1)

Modelling Approach

Ordinary differential equation model (13)

Lab affiliation

Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (35)
University of Victoria (22)
Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark (13)
USDA-ARS (10)
CNIO (9)
Institute of Molecular Biology (IMB), Mainz, Germany (8)
The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China (7)
Basic Immune System of Plants / Protein Mass Spectrometry Max Planck Institute for Plant Breeding Research Carl-von-Linne-Weg 10, 50829 Cologne, Germany (6)
Center for Neuroscience and Cell Biology – University of Coimbra (6)
Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, Spain (6)
Keck MS & Proteomics Resource Yale School of Medicine (6)
School of Biochemistry, Faculty of Life Sciences, University of Bristol,UK (6)
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences (6)
Ghent University, Department of Plant Biotechnology and Bioinformatics, Technologiepark 71, 9052 Ghent, Belgium VIB Center for Plant Systems Biology, Technologiepark 71, 9052 Ghent, Belgium (5)
Indiana University School of Medicine (5)
Industrial Biotechnology & Biocatalysis Group, Biotechnology Laboratory, School of Chemical Engineering, National Technical University of Athens, Athens, Greece (5)
Institut Pasteur (5)
Instituto de Investigaciones Sanitarias de Santiago de Compostela (5)
Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (5)
1 Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, China 2 Department of Toxicology, Fujian Center for Evaluation of New Drug, Fujian Medical University, Fuzhou, China (4)
Associate Professor, Department of Biology, Massachusetts Institute of Technology and Whitehead Institute of Biomedical Research (4)
Biotechnology Research Center, No.2 Tiansheng Road, BeiBei District, Chongqing, 400715,P.R.China (4)
Center for Neuroscience and Cell Biology (4)
Computational and Experimental Biology Group NOVA MEDICAL SCHOOL / FACULDADE DE CIÊNCIAS MÉDICAS UNIVERSIDADE NOVA DE LISBOA Rua Câmara Pestana, 6-6A | 1150-082 Lisboa Portugal (4)
Core Facility Proteomics, Department of Clinical Chemistry, University Medical Center Goettingen, Germany (4)
Department of Cardiovascular Medicine, Center for Circadian Metabolism and Cardiovascular Disease, Southwest Hospital, Army Medical University; Chongqing, China. (4)
Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, United States (4)
Farnusch Kaschani, Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (4)
Institute of Plant Genetics, Leibniz Universitaet Hannover, Germany (4)
TIGEM (4)

IsPrivate

False (13)

Classification

fungi (1)
protozoa (1)
bacteria (1)

Modification

4x(15)N labeled L-arginine (8)
2x(15)N labeled L-lysine (7)
15.994915 (6)
-17.026549 (4)
4-tetrahydrothiazine-3-carboxylic acid (4)
57.021464 (4)
42.010565 (3)
N6 (2)
+3amu) (1)
3x(2)H labeled N6-acetyl-L-lysine (1)
4 (1)
45.029395 (1)
47.036105 (1)
4x(2)H labeled dimethylated residue (1)
58.005479 (1)
79.966331 (1)
N6-dimethyl-L-lysine (1)
Not available (1)

Study type

Transcription profiling by array (44)
RNA-seq of coding RNA (7)
ChIP-seq (5)
Unknown experiment type (4)
Methylation profiling by high throughput sequencing (2)
Cell line - High-throughput sequencing (1)
Transcription profiling by tiling array (1)
RNAi profiling by array (1)
Comparative genomic hybridization by array (1)
Other (1)
MicroRNA profiling by array (1)
Methylation profiling by array (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2025 (301)
2022 (235)
2021 (229)
2023 (213)
2024 (175)
2020 (152)
2018 (150)
2019 (142)
2017 (122)
2015 (114)
2016 (110)
2014 (91)
2010 (66)
2013 (64)
2026 (52)
2012 (52)
2011 (51)
2008 (30)
2009 (23)
2007 (18)
2006 (16)
2005 (13)
2004 (5)
2003 (5)
2002 (4)
2000 (4)
2001 (2)
1999 (1)
1993 (1)

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OsNOA1 functions in a threshold-dependent manner to regulate chloroplast proteins in rice at lower temperatures

While our earlier microarray analysis identified a number of possible candidate genes, which may be involved in OsNOA1 function (Yang et al., 2011a), a complementary study of the rice proteome profiles under the same condition has the potential to yield new insights into the biological functions of ...

ORGANISM(S): Oryza sativa (Rice)

2018-03-02 | PXD005841 | Pride

RELMβ Sets the Threshold for Microbiome-Dependent Oral Tolerance

PRJNA914413 | ENA

Astrocyte Fabp7 modulates seizure threshold and activity-dependent gene expression in mouse brain

PRJNA1134245 | ENA

Predicting the invasiveness of threshold-dependent gene drives.

Not available

S-EPMC12667978 | biostudies-literature

High apoptotic threshold mediates p53 dependent decision between arrest and apoptosis

In response to stress, the p53 tumor suppressor induces arrest or apoptosis by transcriptionally regulating genes that mediate these processes. It has been proposed that the levels of p53 can influence the choice between these different outcomes, but the mechanisms involved are not clear. To gain me...

ORGANISM(S): Homo sapiens

2011-07-19 | E-GEOD-30753 | biostudies-arrayexpress

pH-dependent binding engineering reveals an FcRn affinity threshold that governs IgG recycling.

Not available

S-EPMC4326836 | biostudies-literature

Homo sapiens

High apoptotic threshold mediates p53 dependent decision between arrest and apoptosis

PRJNA144127 | ENA

Mechanotransduction of ultrasound is frequency dependent below the cavitation threshold.

Not available

S-EPMC4183372 | biostudies-literature

Adaptive Layer-Dependent Threshold Function for Wavelet Denoising of ECG and Multimode Fiber Cardiorespiratory Signals.