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TranscriptomicsTranscription profiling of human tetracycline-regulated cell line expressing an NF-kB inhibitor to systematically identify NF-kB dependent genes
TNF time course series of HelA tet off cells cultured in presence or absence of Dox; TNF is a pro-inflammatory cytokine that controls expression of inflammatory genetic networks. Although the Nuclear Factor-kB (NF-kB) pathway is crucial for mediating cellular TNF responses, the complete spectrum of...
ORGANISM(S): Homo sapiens 
2007-09-07 | E-GEOD-2624 | biostudies-arrayexpress
UnknownThe Effects of Disinfection Byproduct 2,6-Dichloro-1,4-benzoquinone on the Cyanobacterium <i>Microcystis aeruginosa</i>: From the Perspectives of Biochemistry and Non-Targeted Metabolomics.
Not available
S-EPMC11768523 | biostudies-literature
MetabolomicsBifidobacterium animalis subsp. lactis BD1 restores neurotransmitter homeostasis in chronically stressed mice via tryptophan metabolic reprogramming

Background: Chronic psychological stress is a major precipitating factor for neuropsychiatric disorders, yet the underlying mechanisms remain incompletely understood. The gut-brain axis has emerged as a critical regulator of mood and behavior, but how specific commensal microbes modulate host neu...

2025-10-23 | MTBLS13208 | MetaboLights
ProteomicsHuman cholangiocarcinoma LC-MS/MS
We studied the effect of Ser30 with or without O-GlcNAc modification on K18 protein and its co-immunoprecipitated proteins in cholangiocarcinoma cells.The lysates from HuCCT1 shK18 stable cell line transfected with FLAG-K18-WT or FLAG-K18-S30A were captured with anti-FLAG beads, and then subjected t...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD048144 | Pride
Hucct1 cells Proteomics K18 
UnknownScreening of salt tolerance of maize (Zea mays L.) lines using membership function value and GGE biplot analysis.
Not available
S-EPMC10832624 | biostudies-literature
ProteomicsHuman cholangiocarcinoma LC-MS/MS
The glycosylation landscape of Human cholangiocarcinoma (CCA), and how it affects CCA diagnosis and prognosis, has recently emerged as an appealing research field.In this study, we used chemical glycoproteomic analysis Click-iG for systematic profiling of intact glycopeptides in CCA and HIBEpiC cell...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD048188 | Pride
Glycoproteomics Click-ig Cholangiocarcinoma 
MetabolomicsDynamic metabolic and transcriptomic profiling reveals the biosynthetic characteristics of hydroxycinnamic acid amides (HCAAs) in sunflower pollen

Sunflower pollen is a natural nutritious food with a long history and multiple functions, however, the main chemical components apart from flavonoids and their biosynthesis processes have not been thoroughly investigated. In this study, seven hydroxycinnamic acid amides (HCAAs) (1-7) abundant in ...

2021-10-15 | MTBLS3075 | MetaboLights
MetabolomicsComparison of the Metabolic Profiles in the Plasma and Urine Samples Between Autistic and Typically Developing Boys: A Preliminary Study
Background: Autism spectrum disorder (ASD) is defined as a pervasive developmental disorder which is caused by genetic and environmental risk factors. Besides the core behavioral symptoms, accumulated results indicate children with ASD also share some metabolic abnormalities. Objectives:
2022-03-02 | MTBLS2421 | MetaboLights
UnknownA de novo silencer causes elimination of MITF-M expression and profound hearing loss in pigs.
Not available
S-EPMC4922063 | biostudies-literature
MetabolomicsGut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
2021-12-08 | MTBLS3174 | MetaboLights
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