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We used a chronic unpredicted mild stress (CUMS) protocol to separate depression-susceptible and stress-insensitive rat subgroups. Differential proteomes in the hippocampus were analyzed based on isobaric tags for relative and absolute quantitation (iTRAQ) labeling combined with mass spectrometry.
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD025773 | Pride
Acupuncture treatment is based on acupoint stimulation; however, the biological basis is not understood. We stimulated one acupoint with catgut embedding (CEP) for 8 weeks and then used isobaric tags for relative and absolute quantitation to screen proteins with altered expression in adjacent acupoi...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-16 | PXD024018 | Pride
We developed a multidimensional proteomic strategy to profile the glycosylated secreted and plasma membrane (S-PM) proteome of 100 human pancreatic tissue samples to an unprecedented depth, define cell-type origins of these S-PM proteins through spatial proteomics, and identify potential paracrine c...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-08-19 | PXD048644 | Pride
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