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MetabolomicsSupplementation of Bacillus sp. DU-106 reduces hypercholesterolemia and ameliorates gut dysbiosis in high-fat diet rats

Gut microbiota modulation by a probiotic is a novel therapy for hypercholesterolemia mitigation. This study initially investigated the potential hypocholesterolemic effect of Bacillus sp. DU-106 in hypercholesterolemic rats and explored its potential relation with gut microbiota. Sprague-Dawley r...

2021-04-08 | MTBLS1168 | MetaboLights
ProteomicsGeneration of a deep mouse brain spectral library for transmembrane proteome profiling in mental disease models
The establishment of a high-quality mouse brain transmembrane proteins spectral library enables in-depth profiling of the proteins across multiple brain regions. DIA data analysis, combining different search pipeline based on the spectral library, discovered a new GPCR regulator which was associated...
ORGANISM(S): Mus Musculus 
2023-11-26 | PXD047251 |
ProteomicsLysine 2-hyroxyisobutyrylome, acetylome and succinylome in prokaryotes
identification of lysine 2-hyroxyisobutyrylome, acetylome and succinylome in prokaryotes
ORGANISM(S): Proteus Mirabilis Atcc 29906 Escherichia Coli 
2019-04-04 | PXD013377 |
ProteomicsMouse brain tissue proteomics-Shui group
DIA and PRM raw data of mouse brain tissues. R1: Cerebellum, R2: Midbrain, R3: Spinal cord
ORGANISM(S): Mus Musculus 
2019-11-26 | PXD016441 |
ProteomicsIdentification of the key components involving in cyclic di-GMP signaling regulation of virulence that is mediated by the signal receptor Filp and its interactor PilZX3 in Xanthomonas oryzae pv. oryzae
The downstream regulatory proteins of Filp and PilZX3 were analyzed by isobaric tag for relative and absolute quantitation (iTRAQ)
ORGANISM(S): Xanthomonas Oryzae Pv. Oryzae Pxo99a 
PXD015734 |
ProteomicsDNA-guided Photoactivatable Probe-based Chemical Proteomics Reveals the Reader Protein of mRNA Methylation
We report a DNA templated chemistry and photo-crosslinking based method to detect the readers of mRNA modification. By use of N6-methyladenosine (m6A), we illustrated that this method can be successfully utilized for labelling and enriching the readers of mRNA modification, as well as for the discov...
ORGANISM(S): Homo Sapiens 
PXD019480 |
ProteomicsIdentification of ECT2-containing protein complex
Cellular extracts from HeLa cells expressing FLAG-ECT2 were immunopurified with anti-FLAG affinity beads and eluted with FLAG peptide. The eluates were resolved on SDS/PAGE and silver stained, followed by mass spectrometric analysis.
ORGANISM(S): Homo Sapiens 
2021-06-29 | PXD026977 |
ProteomicsSILAC-based quantitative mass spectrometry analysis of RPA1-containing protein complex
SILAC-based quantitative mass spectrometry analysis of RPA1-containing protein complex
ORGANISM(S): Homo Sapiens 
2021-08-25 | PXD028105 |
ProteomicsNuclear condensation of CDYL links histone crotonylation and cystogenesis in autosomal dominant polycystic kidney disease
We identify the Kcr sites on histones that are targeted by CDYL in ADPKD cells (WT9-12 cells). We chose to knock out CDYL in WT 9-12 cells (CDYL KO) through CRISPR/Cas9-mediated gene editing to increase the overall levels of histone Kcr. We quantified Kcr modifications on different histone residues ...
ORGANISM(S): Homo Sapiens 
2022-01-17 | PXD031029 |
ProteomicsSILAC experiments profiling of the proteome of WT and CobB KO E.coli
SILAC experiments profiling of the proteome of WT and CobB KO E.coli
ORGANISM(S): Escherichia Coli 
2021-12-11 | PXD030345 |
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