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TranscriptomicsTranscription profiling of rat muscle samples from reinnervated subjects
Three male 8-week-old Wistar rats were used. The peroneal nerve of the animals was transected and sutured to the biceps femoris muscle. Four weeks later, the proximal stump was sutured to the distal stump. The animals survived for 8 weeks. All experiments were performed under Ketanest (ketamine hydr...
ORGANISM(S): Rattus norvegicus 
2007-11-03 | E-GEOD-2566 | biostudies-arrayexpress
TranscriptomicsTibialis anterior muscle of myostatin null mice treated with clenbuterol
Transcription profiling of skeletal muscle (tibialis anterior) of 5-week-old male wild type and myostatin null mice given ad libitum access to 20ppm clenbuterol hydrochloride in drinking water or plain tap water for 2 weeks. The objective of the study was to determine overlap in the mechanisms of mu...
ORGANISM(S): Mus musculus 
2014-02-03 | E-GEOD-27577 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Rattus norvegicus extraocular and tibialis anterior skeletal muscle samples
The extraocular muscles (EOM) are anatomically and physiologically distinct from other skeletal muscles. EOM are preferentially affected in mitochondrial myopathies, but spared in Duchenne's muscular dystrophy. The anatomical and pathophysiological properties of EOM have been attributed to their uni...
ORGANISM(S): Rattus norvegicus 
2007-10-10 | E-GEOD-471 | biostudies-arrayexpress
TranscriptomicsEffect of spermine oxidase overexpression on skeletal muscle mRNA expression.
For additional details see Bongers et al, Spermine Oxidase Maintains Basal Skeletal Muscle Gene Expression and Fiber Size, and Is Strongly Repressed by Conditions that Cause Skeletal Muscle Atrophy . Am J Physiol Endocrinol Metab. 2014 [under review] Bilateral tibialis anterior muscles of C57BL/6 m...
ORGANISM(S): Mus musculus 
2014-12-04 | E-GEOD-63006 | biostudies-arrayexpress
TranscriptomicsCircadian transcriptome of fast tibialis anterior (TA) and slow soleus (SOL) skeletal muscles from muscle-specific Bmal1 KO and control Cre- littermates
To investigate the role of the circadian clock gene Bmal1 in skeletal muscle, we compared the circadian transcriptomes of fast tibialis anterior (TA) and slow soleus (SOL) skeletal muscles from muscle-specific Bmal1 KO (mKO) and their control Cre- littermates (Ctrl). Keyword: Circadian Transcriptome...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-43071 | biostudies-arrayexpress
TranscriptomicsEffect of p21 overexpression on skeletal muscle mRNA expression.
For additional details see Bongers et al, Spermine Oxidase Maintains Basal Skeletal Muscle Gene Expression and Fiber Size, and Is Strongly Repressed by Conditions that Cause Skeletal Muscle Atrophy . Am J Physiol Endocrinol Metab. 2014 [under review] Bilateral tibialis anterior muscles of C57BL/6 m...
ORGANISM(S): Mus musculus 
2014-12-04 | E-GEOD-63007 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of PAX7+ cells isolated from injured Tibialis Anterior muscles of mice exposed to hypoxic versus normoxic atmosphere
Acute muscle injury was induced by cardiotoxin intramuscular injection in the tibialis anterior (TA) of 8-week-old Tg:Pax7nGFP mice. Mice were then housed in standard normoxic atmosphere (21%O2) or in a normobaric hypoxic chamber (10%O2), from 0 to 7 days post-injury (dpi). FACS-sorted PAX7+ (GFP+) ...
ORGANISM(S): Mus musculus 
2025-11-20 | E-MTAB-16208 | biostudies-arrayexpress
TranscriptomicsDysregulated gene expression in Mef2a knockout mice subjected to cardiotoxin-induced muscle injury
We identified genes expressed in mouse skeletal muscle, during the process of muscle regeneration after injury, which are dysregulated in the absence of Mef2a expression. MEF2A is a member of the evolutionarily conserved MEF2 transcription factor family which has known roles in cardiac muscle develo...
ORGANISM(S): Mus musculus 
2013-02-12 | E-GEOD-41871 | biostudies-arrayexpress
TranscriptomicsFiber and NMJ / synaptic gene expression comparisons in rat extraocular muscle (EOM) and tibialis anterior (TA) muscle.
Purpose: To examine and characterize the expression profile of genes expressed at the neuromuscular junctions (NMJs) of extraocular muscles (EOMs) in comparison to the NMJs of tibialis anterior muscle (TA). Methods: Adult rat rectus EOMs and TAs were dissected, flash-frozen, serially sectioned and ...
ORGANISM(S): Rattus norvegicus 
2010-04-28 | E-GEOD-15737 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse masseter and tibialis anterior muscles to determine expression differences between muscle groups
Masseter and Tibialis anterior muscles from adult female control mice to determine expression differences between muscle groups
ORGANISM(S): Mus musculus 
2007-10-11 | E-MEXP-1288 | biostudies-arrayexpress
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