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ProteomicsBorrelia burgdorferi infected Ixodes scapularis nymph saliva proteome
Lyme disease (LD) is one of the most important human vector-borne diseases in North America. Since transmission of Borrelia burgdorferi (Bb), the causative agent of LD, is influenced by yet unknown tick saliva proteins (TSP), the discovery and characterization of such TSPs are highly sought after fo...
ORGANISM(S): Ixodes scapularis (Black-legged tick) (Deer tick) Borreliella burgdorferi Oryctolagus cuniculus (Rabbit) 
2021-09-10 | PXD023940 | Pride
Borrelia burgdorferi Rabbit host Tick saliva 
ProteomicsIxodes Scapularis tick saliva proteins sequentially secreted every 24h during blood feeding
Ixodes scapularis is the most medically important tick species and transmits five of the 14 reportable human tick borne diseases (TBD) in the USA. This study describes LC-MS/MS identification of 582 tick- and 83 rabbit proteins in saliva of I. scapularis ticks that fed for 24, 48, 72, 96, and 120h, ...
ORGANISM(S): Ixodes scapularis (Black-legged tick) (Deer tick) 
2015-12-11 | PXD003214 | Pride
Tick feeding physiology Tick saliva proteome Ixodes scapularis 
ProteomicsQualitative and quantitative proteomics informed by transcriptomics insight into the proteome of Ornithodoros erraticus adult tick saliva.
Anti-tick vaccines have proved to be an effective and sustainable method for the control of tick infestations and tick-borne diseases with clear advantages over the application of chemical acaricides (Šmit and Postma, 2016; de la Fuente, 2018; Ndawula and Tabor, 2020). Moreover, the efficacy of acar...
ORGANISM(S): Ornithodoros erraticus 
2022-02-17 | PXD027367 | Pride
Lc msms Label free quantitaion Dia Ornithodoros erraticus proteome Swath 
ProteomicsTime-resolved proteomic profile of Amblyomma americanum tick saliva during feeding Running Title: Proteins in tick saliva every 24 h during feeding
Pioneering studies (PXD014844) have identified many interesting molecules by LC-MS/MS proteomics, but the protein databases used to assign mass spectra were based on short Illumina reads of the Amblyomma americanum transcriptome and may not have captured the diversity and complexity of longer transc...
ORGANISM(S): Amblyomma americanum 
2020-01-23 | PXD014844 | Pride
Tick-feeding Ticks Saliva Proteome 
ProteomicsProteomic analysis of exosome-like vesicles isolated from saliva of the tick Haemaphysalis longicornis
In this study, extracellular vesicles were isolated from tick saliva and were analyzed for the presence of proteins. LC-MS/MS identified proteins within tick-derived EVs which may be used by tick in modulating host responses.
ORGANISM(S): Haemaphysalis Longicornis 
PXD018853 |
ProteomicsProteomic analysis of exosome like vesicles isolated from saliva of the tick Haemaphysalis longicornis
In this study, we show for the first time that the tick Haemaphysalis longicornis secretes EVs in saliva that resembles exosomes. EVs were purified from pilocarpine induced saliva of partially engorged H. longicornis ticks. Electron microscopy analysis revealed the presence of exosome-like vesicles ...
ORGANISM(S): Haemaphysalis Longicornis 
PXD020300 |
ProteomicsAnalysis of the Salivary Gland Transcriptome of Unfed and Partially Fed Amblyomma sculptum Ticks and Descriptive Proteome of the Saliva
Ticks are obligate blood feeding ectoparasites that transmit a wide variety of pathogenic microorganisms to their vertebrate hosts. Amblyomma sculptum is vector of Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, the most lethal rickettsiosis that affects humans. It is kno...
ORGANISM(S): Amblyomma sculptum 
2018-10-23 | PXD007852 | Pride
Tran Tick Salivary glands Blood feeding Spotted fever Amblyomma Rna-seq 
UnknownProteome of Rhipicephalus sanguineus tick saliva induced by the secretagogues pilocarpine and dopamine.
Not available
S-EPMC3917560 | biostudies-literature
UnknownA 24-48 h fed Amblyomma americanum tick saliva immuno-proteome.
Not available
S-EPMC4099483 | biostudies-literature
ProteomicsProteomic analysis of saliva of Haemaphysalis longicornis during half blood
Tick saliva, an essential chemical secretion of the tick salivary gland, is indispensable for tick survival owing to the physiological influence it exerts on the host defense mechanisms via the instrumentality of its cocktail of pharmacologically active molecules (proteins and peptides).Here, we per...
ORGANISM(S): Haemaphysalis Longicornis 
2021-12-14 | PXD028182 |
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