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ProteomicsStructural Insights into the Interaction Between Adenovirus 5C Hexon and Human Lactoferrin
Adenovirus (AdV) infection of the respiratory epithelium is common but poorly understood. Human infective species C AdVs, such as HAdV-C5, utilise the Coxsackie-Adenovirus receptor (CAR) for attachment and subsequently integrins for entry. CAR and integrins are however located deep within the tight ...
ORGANISM(S): Homo sapiens (Human) 
2024-02-03 | PXD045900 | Pride
Immune-evasion Cryo-em Adenovirus Lactoferrin Viral-entry 
ProteomicsHigh throughput tear proteomics with data independent acquisition enables biomarker discovery in allergic conditions
The search for pathological biomarkers in biological fluids that can provide valuable insight into an individual’s health status, is a relevant area of research for multiple pathologies. Currently, the use of proteomics for the identification of differences in protein expression profiles between sam...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD067099 | Pride
Diapasef. High-throughput proteomics Tear secretion Biomarkers 
ProteomicsFASN-dependent de novo lipogenesis is required for brain development
Fate and behaviour of neural progenitor cells is tightly regulated during mammalian brain development. Metabolic pathways, such as glycolysis and oxidative phosphorylation, that are required for supplying energy and providing molecular building blocks to generate cells, govern progenitor function. H...
ORGANISM(S): Homo sapiens (Human) 
2022-01-14 | PXD026110 | Pride
Fasn Human Mouse Lipogenesis Brain development Brain organoids 
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