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TranscriptomicsMyeloid Derived Suppressor Cells and Cancer
Transcriptional profiling of FACS-sorted and splenic control mouse cells, comparing splenic cells from FVBneuN vs Neu+ expressing FVBneuN mice with Gr1+ CD11b+ sorted tumor-infiltrating mononuclear or splenic myeloid-derived suppressor cells 4 groups or conditions. Biological replicates: 2 or 3 per ...
ORGANISM(S): Mus musculus 
2010-12-29 | E-GEOD-26289 | biostudies-arrayexpress
TranscriptomicssiRNA profiling of human H157 non-small cell lung carcinoma cells with and without DJ-1 expression knocked-down
DJ-1 expression protects H157 cells from cell death, using siRNA oligomers we knocked down DJ-1 and evaulated gene expression using Affymetrix U133A GeneChip arrays. Experiment Overall Design: H157 cells were transfected every 24 hours with siRNA oligomers for 3 consecutive days, lysed 96 hours afte...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5519 | biostudies-arrayexpress
MetabolomicsArginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
Defective arginine synthesis, due to the silencing of argininosuccinate synthase 1 (ASS1), is a common metabolic vulnerability in cancer, known as arginine auxotrophy. Understanding how arginine depletion kills arginine-auxotrophic cancer cells will facilitate the development of anti-cancer therapeu...
2019-11-07 | MTBLS745 | MetaboLights
TranscriptomicsTranscription profiling of mouse dendritic cells from wild type, CIITA-/- and I-A beta -/- strains representing CIITA-deficient, MHC class II-deficient and control mice
Triplicates preparations of RNA from day 10 DC's. Experiment is described in Wong et al 2003 Nat. Immunol.
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-557 | biostudies-arrayexpress
GenomicsGenetic Heterogeneity of Diffuse Large B Cell Lymphoma

We sequenced exomes of 94 DLBCL tumors and cell lines. 34 of the tumors had paired normal tissue. Our work elucidates commonly occurring gene-coding mutations in DLBCL.

phs000573.v1.p1 | EGA
UnknownViral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimen.
Not available
S-EPMC2745911 | biostudies-literature
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
UnknownSeverity of cardiovascular disease outcomes among patients with HIV is related to markers of inflammation and coagulation.
Not available
S-EPMC4309077 | biostudies-literature
UnknownDevelopment and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study.
Not available
S-EPMC4380415 | biostudies-literature
UnknownDeath following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic.
Not available
S-EPMC10364875 | biostudies-literature
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