Tk - OmicsDI

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Unknown (11996)
Proteomics (258)
Transcriptomics (245)
Genomics (202)
Metabolomics (9)
Models (6)
Clinical (4)
Other (2)
Genomic (1)
Multiomics (1)

Organisms

Homo sapiens (155)
Mus musculus (77)
Arabidopsis thaliana (6)
Schizosaccharomyces pombe (6)
Escherichia coli (5)
Rattus norvegicus (5)
Danio rerio (4)
Sus scrofa (4)
Zea mays (3)
Pseudomonas aeruginosa (3)
Drosophila melanogaster (3)
Macaca nemestrina (2)
Fundulus heteroclitus (2)
Bos taurus (2)
Caenorhabditis elegans (2)
Saccharomyces cerevisiae (2)
Leishmania infantum (2)
Thermococcus kodakarensis (2)
Ciona intestinalis (2)
Tetranychus urticae (2)
Escherichia coli K-12 (1)
Ovis aries (1)
Eukaryota (1)
Orchesella cincta (1)
Streptomyces rimosus (1)
Pimephales promelas (1)
Folsomia candida (1)
Neurospora crassa (1)
Trypanosoma brucei brucei (1)
Escherichia coli BW25113 (1)

Organisms

Homo sapiens (35)
Mus musculus (14)
Hydrogenobacter thermophilus TK-6 (3)
Schizosaccharomyces pombe (2)
drinking water metagenome (2)
Pediococcus pentosaceus (2)
Sus scrofa (2)
Bacillus sp. TK-2 (1)
Clostridium pasteurianum TK (1)
HSV-tk-containing vector pGTK3 (1)
Drosophila sp. 1 TK-2016 (1)
Panonychus ulmi (1)
Tieghemostelium lacteum (1)
Alteromonas sp. TK-46(2) (1)
Leishmania infantum (1)
Pleurodeles waltl (1)
Camponotus fellah (1)
Thermococcus kodakarensis (1)
Streptomyces albus (1)
Centaurea solstitialis (1)
Pimephales promelas (1)
Aquarana catesbeiana (1)
bacterium U1378_B11H3_sediment (1)
Lacticaseibacillus paracasei (1)
Tetranychus urticae (1)
human blood metagenome (1)
Aspergillus oryzae (1)
Drosophila melanogaster (1)
Zea mays (1)
human oral metagenome (1)

Repository

biostudies-arrayexpress (237)
pride (225)
ENA (157)
geo (42)
EGA (16)
MassIVE (14)
MetaboLights (9)
PanoramaPublic (6)
BioModels (5)
jPOST (5)
iProX (3)
GPMDB (2)
PeptideAtlas (2)
dbGaP (1)
FAIRDOMHub (1)
PAXDB (1)

Tissue

Blood (56)
Cell culture (27)
Epithelial cell (19)
T cell (12)
B cell (11)
Blood plasma (9)
Neutrophil (8)
Lung (7)
Bone marrow (5)
Leaf (5)
Monocyte (5)
Permanent cell line cell (5)
Saliva (5)
Endosperm (4)
Hepatocyte (4)
Peripheral blood mononuclear cell (4)
Platelet (4)
Blood cell (3)
Brain (3)
Cerebrospinal fluid (3)
Endothelial cell (3)
Kidney (3)
Lymph node (3)
Primary cell (3)
Urine (3)
Blood serum (2)
Cell suspension culture (2)
Cytotoxic T cell (2)
Eye (1)
Urine (1)

Disease

Disease free (60)
Lymphoma (10)
Breast cancer (6)
Chronic myeloid leukemia (3)
Lung cancer (3)
Not Available (2)
Alzheimer's disease (2)
FTDALS1 (2)
Gray platelet syndrome (2)
Lung adenocarcinoma (2)
Non-small cell lung carcinoma (2)
Pancreatic cancer (2)
Prostate adenocarcinoma (2)
Pulmonary neuroendocrine tumor (2)
Liver disease (1)
Normal (1)
Invasive carcinoma (1)
Normal (1)
Mucositis (1)
Malignant neoplasm of colon, unspecified (1)
Carcinoma (1)
Neoplasms (1)
Brain glioblastoma multiforme (1)
Cerebrovascular disease (1)
Cervical cancer (1)
Colon cancer (1)
Colorectal cancer (1)
Frontotemporal dementia (1)
Head and neck squamous cell carcinoma (1)
Inflammation (1)

Technology Type

Mass Spectrometry (225)
Shotgun proteomics (84)
Top-down proteomics (59)
Affinity purification coupled with mass spectrometry proteomics (27)
Bottom-up proteomics (25)
Data-dependent acquisition (14)
Gel-based experiment (12)
SWATH MS (10)
Mass spectrometry (8)
SRM/MRM (7)
Chemical cross-linking coupled with mass spectrometry proteomics (6)
Data-independent acquisition (5)
Mass spectrometry assay (2)
HDMSE (2)
Illumina HiSeq 2000, Illumina_2.5M (1)
Illumina HiSeq 2000 (1)
NMR spectroscopy (1)
Metaproteomics (1)
Proteogenomics (1)

Instrument Platform

Orbitrap Exploris 480 (4)
LTQ Orbitrap Velos (4)
Liquid Chromatography MS - positive - reverse phase (4)
Liquid Chromatography MS - negative - reverse phase (4)
Orbitrap Fusion (3)
Orbitrap Fusion Lumos (3)
Illumina NovaSeq 6000 (2)
Illumina HiSeq 2000 (2)
Instrument (2)
Q Exactive (2)
Liquid Chromatography MS - negative - hilic (2)
Liquid Chromatography MS - positive - hilic (2)
(Make:Affymetrix Scanner,Model:) (1)
Spectronic Helios Alpha UV-Vis spectrophotometer (1)
GenePix 4000B [Axon Instruments] (1)
Ion Torrent Proton (1)
Illumina HiSeq 4000 (1)
NextSeq 500 (1)
Orbitrap Eclipse (1)
Orbitrap Fusion ETD (1)
TripleTOF 5600 (1)
Flow injection analysis MS – POS (1)
Liquid Chromatography MS – NEG (1)
Liquid Chromatography MS – POS (1)
Nuclear Magnetic Resonance (NMR) - (1)
Liquid Chromatography MS - alternating - hilic (1)
Liquid Chromatography MS - alternating - reverse phase (1)
LTQ (1)

Publication Date

2022 (89)
2010 (45)
2025 (35)
2012 (35)
2015 (33)
2021 (32)
2023 (30)
2014 (27)
2011 (27)
2016 (23)
2020 (22)
2013 (22)
2019 (19)
2009 (17)
2024 (16)
2018 (15)
2008 (15)
2026 (13)
2017 (10)
2005 (7)
2004 (6)
2007 (4)
2006 (2)
2001 (1)

UNIPROT ID/AC

P02768 (1)
P07659 (1)
P00573 (1)
P42212 (1)
1433B_HUMAN (1)
1433E_HUMAN (1)
1433F_HUMAN (1)
1433G_HUMAN (1)
1433S_HUMAN (1)
1433T_HUMAN (1)
1433Z_HUMAN (1)
6PGD_HUMAN (1)
6PGL_HUMAN (1)
9606.ENSP00000322421 (1)
9606.ENSP00000347168 (1)
9606.ENSP00000348924 (1)
9606.ENSP00000352119 (1)
9606.ENSP00000352627 (1)
9606.ENSP00000356391 (1)
9606.ENSP00000366679 (1)
9606.ENSP00000366956 (1)
9606.ENSP00000366962 (1)
9606.ENSP00000366974 (1)
9606.ENSP00000367034 (1)
9606.ENSP00000382982 (1)
9606.ENSP00000415840 (1)
9606.ENSP00000417240 (1)
9606.ENSP00000421191 (1)
9606.ENSP00000443017 (1)
9606.ENSP00000445633 (1)

ENSEMBL ID

ENSG00000170477 (2)
ENSG00000229353 (1)

CHEBI ID

CHEBI:15891 (6)
CHEBI:15354 (5)
CHEBI:16977 (4)
CHEBI:6650 (4)
CHEBI:18019 (4)
CHEBI:15971 (4)
CHEBI:16704 (4)
CHEBI:16015 (4)
CHEBI:16414 (4)
CHEBI:17895 (4)
CHEBI:16990 (3)
CHEBI:17535 (3)
CHEBI:17768 (3)
CHEBI:17431 (3)
CHEBI:27410 (3)
CHEBI:16765 (3)
CHEBI:27389 (3)
CHEBI:40410 (3)
CHEBI:48430 (3)
CHEBI:18132 (3)
CHEBI:49033 (3)
CHEBI:16040 (3)
CHEBI:17126 (3)
CHEBI:16797 (3)
CHEBI:27891 (3)
CHEBI:17443 (3)
CHEBI:27594 (1)
CHEBI:33839 (1)
CHEBI:33697 (1)
CHEBI:33699 (1)

Metabolite Name

Diethanolamine (3)
Adenosine (3)
Chlorobenzene (2)
Tryptamine (2)
2'-deoxycytidine (2)
Taurine (2)
N-acetylglutamate (2)
Guanosine (2)
Cytosine (2)
Cytidine (2)
Cysteine (2)
Arginine (2)
Glutamine (2)
Glycine (2)
Spermidine (2)
Betaine (2)
L-Lysine (2)
L-Proline (2)
Kynurenic acid (2)
Phytosphingosine (2)
Carnitine (2)
Acetylcarnitine (2)
Choline (2)
Taurine (2)
Tyramine (2)
Cytosine (2)
Malonic acid (2)
L-Serine (2)
Xanthine (2)
Creatine (2)

First Public Date

2026 (28)
2014 (25)
2025 (24)
2024 (18)
2023 (14)
2021 (11)
2022 (9)
2017 (6)
2019 (5)
2016 (4)
2015 (4)
2013 (4)
2018 (3)
2020 (2)

Modelling Approach

Ordinary differential equation model (5)

Study status

Completed (2)
Terminated (1)
Active, not recruiting (1)

Lab affiliation

Departments of Chemical and Biological Engineering, Chemistry, and Molecular Biosciences, the Chemistry of Life Processes Institute, and the Proteomics Center of Excellence, Northwestern University, Evanston, Illinois 60208, United States (55)
Institute of Functional Epigenetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany. (5)
School of Chemistry and Molecular Biosciences, The University of Queensland, Australia (5)
The Institute of Medical Science, The University of Tokyo (4)
GlycoProteomics Laboratory, Department of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Avenida Lineu Prestes 1374, CEP 05508-000, Sao Paulo, Brazil (3)
Institute of Functional Epigenetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany (3)
Associate Professor Regional Centre for Biotechnology (2)
Centre de Recherche en Cancérologie de Marseille, CRCM Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli Calmettes 27 Boulevard Leï Roure CS30059 13273 Marseille Cedex 09 France (2)
Department of Biochemistry UT Southwestern Medical Center (2)
Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA (2)
Faculty of Biosciences and Aquaculture, Nord University, Bodø, Norway (2)
Functional Proteomics Laboratory, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, India (2)
Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany (2)
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore (2)
Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad 121001, INDIA. (2)
School of Molecular and Cellular Biology, Faculty of Biological Sciences, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom (2)
Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA (2)
Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, Karnataka, India (2)
1 Precision Medicine Programme, Yong Loo Lin School of Medicine (YLLSoM), National University of Singapore, 2 NUS Centre for Cancer Research, National University of Singapore, 3 Department of Biochemistry, YLLSoM, National University of Singapore (1)
1Neonatal Research, Murdoch Children’s Research Institute, Parkville, Australia 2Department of Paediatrics, University of Melbourne, Melbourne, Australia (1)
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA (1)
Additional Professor, Department of Medical Oncology (Lab.), Dr B.R.A.I.R.C.H., AIIMS, New Delhi (1)
Animal Genomics Lab, Animal Biotechnology Centre, National Dairy Research Institute, Karnal, Haryana, India (1)
Arvinas Operations, Inc., 5 Science Park, 395 Winchester Avenue, New Haven, Connecticut 06511 United States (1)
Associate Professor, Department of Microbiology and Immunology (1)
Associate Professor, Pediatrics Adjunct Associate Professor, Microbiology and Global Health Affiliate Member: FHCRC Consortium University of Washington Seattle Childrens Research Institute 1900 9th Ave SeattleWA 98101-1304 (1)
Beijing Proteome Research Center (1)
Bioanalytical Mass Spectrometry, Max Planck Institute for Multidisciplinary Sciences, Germany Bioanalytics, University Medical Center Goettingen, Germnay (1)
Biochemistry, YLL School of Medicine, NUS (1)
Biotechnology Center, National Chung-Hsing University, Taichung 402, Taiwan (1)

Keyword

Flucytosine (1)
Advanced/metastatic colorectal carcinoma (1)
Uridine Phosphorylase Inhibitor (1)
5 FU/ LU (1)
Chemotherapy (1)

IsPrivate

False (5)

Model Flag

Non Kinetic (1)

Classification

protozoa (2)
fungi (1)
bacteria (1)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)
N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (153)
RNA-seq of coding RNA (23)
ChIP-seq (20)
ChIP-chip by tiling array (9)
Methylation profiling by array (7)
Unknown experiment type (6)
Comparative genomic hybridization by array (4)
Interventional (4)
DNA-seq (3)
Proteomic profiling by array (2)
Transcription profiling by MPSS (1)
Transcription profiling by tiling array (1)
RNAi profiling by array (1)
Transcription profiling by RT-PCR (1)
Other (1)
MicroRNA profiling by array (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2022 (1303)
2021 (1179)
2025 (1156)
2023 (1121)
2024 (1005)
2020 (977)
2019 (765)
2018 (683)
2016 (601)
2017 (589)
2015 (526)
2014 (465)
2013 (307)
2012 (290)
2011 (244)
2010 (243)
2009 (155)
2026 (149)
2008 (129)
2007 (85)
2006 (61)
2004 (46)
2005 (44)
2003 (29)
2002 (21)
2000 (20)
2001 (17)
1999 (10)
1998 (8)
1997 (5)

Location

India (2)
South Korea (1)
Spain (1)
Belgium (1)
France (1)

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Clostridium pasteurianum TK strain:TK

Clostridium pasteurianum TK strain:TK Genome sequencing

PRJNA206427 | ENA

NP-18 vs. NP-18AR transcriptional profile upon treatment with TK/GCV

Pancreatic cancer-derived cells NP-18 underwent four rounds of treatment with increasing doses of an adenoviral vector encoding TK enzyme and GCV. Surviving cells were termed NP-18AR and displayed decreased sensitivity to treatment. This experiment analyses the transcriptomic effect of TK/GCV treatm...

ORGANISM(S): Homo sapiens

2010-07-16 | E-GEOD-17137 | biostudies-arrayexpress

Hydrogenobacter thermophilus TK-6

Hydrogenobacter thermophilus TK-6 Genome sequencing

PRJNA41547 | ENA

Comparative analysis of gene expression profiles between the ovary treated with or without Ci-TK

Tachykinins (TKs) and their receptors have been shown to be expressed in the mammalian ovary. However, the biological roles for ovarian TKs have yet to be verified. Ci-TK and Ci-TK-R, characterized from the protochordate (ascidian), Ciona intestinalis, are prototypes of vertebrate TKs and their rece...

ORGANISM(S): Ciona intestinalis

2010-05-22 | E-GEOD-8821 | biostudies-arrayexpress

Bacillus sp. TK-2

Bacillus sp. TK-2 Genome sequencing and assembly

PRJNA689918 | ENA

Hydrogenobacter thermophilus TK-6

This strain will be used for comparative genome analysis

PRJDA34131 | ENA

Mapping Tyrosine Kinase Based on TK Activity Representing Peptide Library Reveals a Role for SRC in H1975 Drug Resistance

a method to assay TK activity and its application to investigate the mechanism of anti-cancer drug resistance

ORGANISM(S): Homo Sapiens

2022-02-28 | PXD031904 |

Expression profiling of WT and aSMA-TK wounds

PRJNA741477 | ENA

Tieghemostelium lacteum strain:TK

Tieghemostelium lacteum strain:TK Genome sequencing and assembly

PRJNA305239 | ENA

Quantitative proteomic analysis of gastric cancer cells treated by bifidobacterium infantis-mediated herpes simplex virus-TK/ganciclovir.

MKN-45 cells were treated with PBS, BF-TK, BF/GCV or BF-TK/GCV for 48 h (GCV, 167 µg/ml), respectively. BF-TK (n = 3), BF/GCV (n = 3) or BF-TK/GCV (n = 3) groups were analyzed in triplicate.

ORGANISM(S): Homo sapiens (Human)

2023-10-24 | PXD042044 | Pride

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