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UnknownGenetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5.
Not available
S-EPMC4178035 | biostudies-literature
UnknownStarvation-inactivated MTOR triggers cell migration via a ULK1-SH3PXD2A/TKS5-MMP14 pathway in ovarian carcinoma.
Not available
S-EPMC10621272 | biostudies-literature
ProteomicsTks5 protein Interactome
Tks5 (SH3PXD2A) is essential for the formation of invadopodia – specialized membrane microdomains that are essential for breast cancer cell migration in extracellular matrix (mostly collagen type I) and invasion. Tks5 is a large scaffold protein and its function at invadopodia is believed to come fr...
ORGANISM(S): Homo sapiens (Human) 
2020-07-08 | PXD011632 | Pride
Breast cancer Invadopodia Sh3pxd2a Invasion Tks5 
ProteomicsA proximity-labeling proteomic approach to investigate invadopodia molecular landscape in breast cancer cells
Invadopodia constitute a specialized machinery required for invasive tumor cells to travel through basement membranes and the interstitial matrix, and thus represent a key feature of metastatic cells. Therefore a better understanding of invadopodia biology and characteristics might permit the identi...
ORGANISM(S): Homo sapiens (Human) 
2020-04-24 | PXD015847 | Pride
Actin cytoskeleton Cancer invasion Tks5/sh3pxd2a 
UnknownThe role and regulation of Rab40b-Tks5 complex during invadopodia formation and cancer cell invasion.
Not available
S-EPMC5201011 | biostudies-literature
UnknownNck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.
Not available
S-EPMC2909319 | biostudies-literature
UnknownTks5 interactome reveals endoplasmic-reticulum-associated translation machinery in invadosomes.
Not available
S-EPMC12699180 | biostudies-literature
TranscriptomicsTranscriptional responses of resistant and susceptible fish clones to the bacterial pathogen Flavobacterium psychrophilum
Comparison of the transcriptional response to the bacteria in the pronephros of a susceptible and a resistant line by micro-array analysis five days after infection Four to seven individual fishes have been analyzed for each experimental condition : Infected or Control ; Susceptible or resistant lin...
ORGANISM(S): Oncorhynchus mykiss 
2013-01-02 | E-GEOD-35448 | biostudies-arrayexpress
TranscriptomicsGenotype-specific responses in intestinal lipid metabolism to complete dietary fish oil replacement by vegetable oil in Atlantic salmon
As part of a study investigating the effects of genotype on responses to sustainable feeds in Atlantic salmon, a microarray analysis of the intestine transcriptome of two family groups, identified as 'Lean' or 'Fat' (based on flesh lipid content), which were fed a diet containing either 100% fish oi...
ORGANISM(S): Salmo salar 
2012-03-01 | E-TABM-1173 | biostudies-arrayexpress
UnknownInvadopodia-mediated ECM degradation is enhanced in the G1 phase of the cell cycle.
Not available
S-EPMC6826011 | biostudies-literature
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