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The human genome encodes two proteins closely related to transketolase (TKT), transketolase-like protein 1 and 2 (TKTL1 and TKTL2). TKTL1 shares 61% amino acid sequence identity with TKT. More and more evidence suggests a role for TKTL1 in proliferation or cell cycle regulation. Indeed, TKTL1 is ove...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD013309 | Pride
TKTL1: a new candidate gene in nonobstructive azoospermia
The genetic background of the non-obstructive azoospermia (NOA) remains poorly known. However, recent studies employing next generation sequencing techniques were able to uncover some NOA causative genes, among which was the TKTL1 gene. In this article we aim to understand the function of the TKTL1 ...
ORGANISM(S): Homo sapiens 
2025-05-01 | GSE262557 | GEO
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