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This project investigates the impact of N-myristoyltransferase (NMT) inhibition on the myristoylated proteome of Trypanosoma cruzi and human cardiomyocytes in the context of Chagas disease. Human AC16 cardiomyocytes were infected with T. cruzi (CL Brener strain) and treated with the reference NMT in...
ORGANISM(S): Trypanosoma cruzi Homo sapiens (Human) 
2026-01-26 | PXD071927 | Pride
Identification of genes differentially expressed between human CD14+CD16- and CD16+ monocyte-derived macrophages generated in the presence of either GM-CSF (termed GM14 and GM16, respectively) or M-CSF (termed M14 and M16, respectively) Human peripheral CD14+CD16- and CD16+ blood monocytes from thr...
ORGANISM(S): Homo sapiens 
Transcriptional profiling was performed on cells grown in YEPD medium at 28 M-0C to an OD600 nm = 1.8, in case of cells grown in exponential phase; alternatively, cells were growth in 1% N-acetylglucosamine and 50 mM citrate buffer pH6.0 at 28 M-0C for different times points (15, 60 and 180 minutes)...
ORGANISM(S): Yarrowia lipolytica 
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