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MetabolomicsMarine toxins spectral database for dereplication purpose

We present an open access marine toxins spectral database for dereplication purpose using the new tool GNPS MASST.

This interface enables you to search a single MS/MS spectrum against public GNPS spectral libraries including MetaboLights and all public MS/MS datasets.

The database wil...

2020-01-14 | MTBLS599 | MetaboLights
TranscriptomicsTranscription profiling of human HeLa cells treated with major listerial toxin listeriolysin
Upon infection, pathogens reprogram host gene expression. In eukaryotic cells, genetic reprogramming is induced by the concerted activation/repression of transcription factors and various histone modifications that control DNA accessibility in chromatin. We report here that the bacterial pathogen, ...
ORGANISM(S): Homo sapiens 
2008-04-01 | E-MEXP-1078 | biostudies-arrayexpress
TranscriptomicsReceptors are affected by selection with each Bacillus thuringiensis israelensis Cry toxin but not with the full Bti mixture in Aedes aegypti
Bacillus thuringiensis israelensis (Bti) toxins are increasingly used for mosquito control, but little is known about the precise mode of action of each of these toxins, and how they interact to kill mosquito larvae. By using RNA sequencing, we investigated change in gene transcription level and pol...
ORGANISM(S): Aedes aegypti 
2019-05-16 | E-MTAB-7970 | biostudies-arrayexpress
ProteomicsTargeted Mass Spectrometry Analysis of Clostridium perfringens Toxins
Clostridium perfringens is an anaerobic, gram-positive, spore-forming bacterium spread throughout the environment. This bacterium is a common agent in the gastrointestinal tracts of healthy human beings and other mammals. Simultaneously, this agent is one of the most significant producers of toxins ...
ORGANISM(S): Clostridium perfringens Clostridium perfringens 
2019-03-25 | PXD012528 | Pride
Prm  clostridium perfringens  protein toxin  epsilon toxin 
TranscriptomicsHuman colon epithelial treated with Clostridium difficile Toxins A and B
Toxin A and B from Clostridium difficile are the primary virulence factors in Clostridium difficile disease. The changes in gene transcription of human colon epithelial cells were investigated in vitro in order to better understand the many effects of both toxins. HCT-8 cells were treated with 100 n...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29008 | biostudies-arrayexpress
UnknownDevelopment and Validation of a UHPLC-ESI-MS/MS Method for Quantification of Oleandrin and Other Cardiac Glycosides and Evaluation of Their Levels in Herbs and Spices from the Belgian Market.
Not available
S-EPMC7232191 | biostudies-literature
ProteomicsIllustrating the Evolution of Toxins within Cnidarian
The aim of this study was to illustrate the breadth of venom evolution in cnidarians and to determine if venom toxins have been co-opted and modified for parasitic lifestyles. Samples representing cnidarian taxa with entirely parasitic life cycles (myxozoans), entirely free-living life cycles, and ...
ORGANISM(S): Buddenbrockia plumatellae Myxobilatus gasterostei Polypodium hydriforme Calvadosia cruxmelitensis 
2020-12-03 | PXD016306 | Pride
Toxins Myxozoa Cnidaria Lc-ms/ms 
GenomicsExpression of E. coli RNase toxins
Expression of E. coli RNase toxins
PRJNA602534 | ENA
ProteomicsA multi-omics approach unravels new toxins with potential antimicrobial, antiviral and antitumoral activities in the venom of Acanthoscurria rondoniae
The Araneae order is considered one of the most successful group among venomous animals in the world. An important factor for this success is the production of venoms, a refined biological fluid rich in proteins, short peptides and cysteine-rich peptides (CRPs). These toxins may present pharmacologi...
ORGANISM(S): Acanthoscurria rondoniae 
2020-07-20 | PXD019343 | Pride
Peptidomics Cysteine-rich peptides Proteomics 33 antimicrobial peptides Antiviral peptides Multi-omics Acanthoscurria rondoniae Antitumoral peptides 
TranscriptomicsE. coli BW25113 K-12 hfq vs. wild-type persister
Persisters are cells which evade stresses like antibiotics and which are characterized by reduced metabolism and a lack of genetic alterations required to achieve this state. We showed previously that MqsR and MqsA of Escherichia coli are a toxin-antitoxin pair that influence cell physiology (e.g.,...
ORGANISM(S): Escherichia coli 
2009-11-07 | E-GEOD-18852 | biostudies-arrayexpress
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