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ProteomicsQuantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells
Reversible protein phosphorylation is one of the most important posttranslational modifications (PTMs) due to its vital role in cellular functions and signaling pathways. Protein phosphorylation is also known to be involved in the regulation of apoptosis. Previously, we have performed a SILAC-based ...
ORGANISM(S): Homo sapiens (Human) 
2017-05-11 | PXD004415 | Pride
: apoptosis Mass spectrometry Phosphorylation Cisplatin Phosphoproteomics 
UnknownGenome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility.
Not available
S-EPMC6366343 | biostudies-literature
TranscriptomicsTranscriptional effects of I-PpoI induced DNA double strand breaks in mouse lymphocytes
DNA double-strand breaks (DSBs) and their repair can cause extensive epigenetic changes. As a result, DSBs have been proposed to promote transcriptional and, ultimately, physiological dysfunction via both cell-intrinsic and cell-non-autonomous pathways. Studying the consequences of DSBs in higher or...
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-74855 | biostudies-arrayexpress
TranscriptomicsPten loss and RAS/MAPK activation cooperate to promote EMT and prostate cancer metastasis initiated from stem/progenitor cells
PTEN loss or PI3K/AKT signaling pathway activation correlates with human prostate cancer progression and metastasis. However, in preclinical murine models, deletion of Pten alone fails to mimic the significant metastatic burden that frequently accompanies the end stage of human disease. To identify...
ORGANISM(S): Mus musculus 
2012-02-28 | E-GEOD-34839 | biostudies-arrayexpress
TranscriptomicsMonitoring of functional gene responses to biostimulation from TCE-contaminated sites using a functional microarray
This SuperSeries is composed of the following subset Series: GSE28606: Monitoring of functional gene responses to ERD (enhanced reductive dechlorination) from four TCE-contaminated sites GSE28608: Monitoring of functional gene responses to biostimulation from a TCE-contaminated site Refer to individ...
ORGANISM(S): groundwater metagenome 
2012-04-02 | E-GEOD-28609 | biostudies-arrayexpress
TranscriptomicsMonitoring of functional gene responses to biostimulation from a TCE-contaminated site
A functional microarray targeting 24 genes involved in chlorinated solvent biodegradation pathways has been developed and used to monitor the gene expression in a contaminated site (site B) under ERD (enhanced reductive dechlorination) treatment. The microarray format provided by NimbleGen and used ...
ORGANISM(S): groundwater metagenome 
2012-04-02 | E-GEOD-28608 | biostudies-arrayexpress
UnknownEvidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.
Not available
S-EPMC3236649 | biostudies-literature
TranscriptomicsMonitoring of functional gene responses to ERD (enhanced reductive dechlorination) from four TCE-contaminated sites
A functional microarray targeting 24 genes involved in chlorinated solvent biodegradation pathways has been developed and used to monitor the gene diversity present in four trichloroethylene (TCE) contaminated sites under ERD (enhanced reductive dechlorination) treatment. The microarray format provi...
ORGANISM(S): groundwater metagenome 
2012-04-02 | E-GEOD-28606 | biostudies-arrayexpress
UnknownEffects of app delivered self hypnosis on stress management.
Not available
S-EPMC12775527 | biostudies-literature
UnknownAdaptive Pressure Control-Continuous Mandatory Ventilation Versus Volume Control-Continuous Mandatory Ventilation: Factors Associated With Initiation, Maintenance, and Adjustment.
Not available
S-EPMC11572997 | biostudies-literature
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