Trans-splicing - OmicsDI

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Transcriptome sequencing to systematically detect trans-splicing in human embryonic stem cells

Trans-splicing occurs post-transcriptionally and generates transcripts that are orderly inconsistent with their corresponding DNA templates. Until recently only exceedingly rare trans-splicing events have been experimentally characterized in the mammalian transcriptomes. Although hundreds to thousan...

ORGANISM(S): Homo sapiens

2014-02-03 | E-GEOD-30557 | biostudies-arrayexpress

Genome-wide map of spliced-leader-led trans-splice sites in Oikopleura dioica

Polycistronic mRNAs transcribed from operons are resolved via the trans-splicing of a spliced leader (SL) RNA. The SL is also frequently trans-spliced to monocistronic transcripts. Using a modified cap analysis of gene expression (CAGE) protocol we mapped sites of SL trans-splicing genome-wide in th...

ORGANISM(S): Oikopleura dioica

2015-01-26 | E-GEOD-50849 | biostudies-arrayexpress

High-resolution genome-wide transcriptomics analysis of O. dioica during recovery from growth arrest

ORGANISM(S): Oikopleura dioica

2015-01-26 | E-GEOD-50848 | biostudies-arrayexpress

Identification of RNAs associated with the Caenorhabditis elegans spliced-leader trans-splicing proteins SNA-2, SNA-3, SNR-2 and SUT-1 proteins by RIP-Seq.

This study aimed to identify RNAs bound to the C. elegans SNA-2, SNA-3, SUT-1 and SNR-2 proteins involved in spliced leader 1 trans-splicing through use of RNA immunoprecipitation sequencing (RIP-Seq). Four IP sample replicates and four control sample replicates were sequenced for each protein.

ORGANISM(S): Caenorhabditis elegans

2024-04-24 | E-MTAB-13193 | biostudies-arrayexpress

Regulatory Divergence in Drosophila revealed by mRNA-seq (trans-splicing)

Deep Sequencing of mRNA from Drosophila melanogaster, Drosophila Sechellia, and their F1 hybrid. These data were generated in a study to analyze the extent and specificity of trans-splicing in Drosophila. mRNA-seq libraies were prepared from poly(A)+ RNA prepared from whole F1 hybrids of D. melanog...

ORGANISM(S): Drosophila melanogaster x Drosophila sechellia

2010-07-19 | E-GEOD-22588 | biostudies-arrayexpress

Multiple intron motifs have redundant functions in trans-splicing of the mod(mdg4) locus

In contrast to canonical cis-splicing, trans-splicing combines exons from two distinct transcripts, yielding chimeric mRNAs. One striking example is the ubiquitously expressed modifier of mdg4 (mod(mdg4)) locus in Drosophila, where all mRNAs spanning over 30 isoforms are generated exclusively by tra...

ORGANISM(S): Drosophila melanogaster (Fruit fly)

2026-05-28 | PXD079014 | Pride