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ProteomicsA mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism
The mini-hairpin shaped nascent peptide that blocks translation termination was found by comprehensive proteomics approach for small ORFs overexpression.
ORGANISM(S): Escherichia Coli 
2025-02-17 | PXD052430 | JPOST Repository
ProteomicsCircadian clock control of ribosome composition promotes rhythmic translation and termination fidelity
We describe circadian clock-dependent changes in ribosome composition in Neurospora crassa depending on cell type, stress, or developmental state. Mass spectrometry of ribosomes isolated at different circadian times identified six ribosomal proteins and one ribosome-associated protein with clock-con...
ORGANISM(S): Neurospora Crassa (ncbitaxon:5141) 
2024-10-15 | MSV000096101 | MassIVE
ModelsFirczuk2013 - Eukaryotic mRNA translation machinery
Firczuk2013 - Eukaryotic mRNA translation machinery This is a model of Saccharomyces cerevisiae mRNA translation which includes the initiation, elongation and termination phases. The model is for 20 condon mRNAs. The building of a multi-factor complex in initiati...
2024-09-02 | BIOMD0000000457 | BioModels
GenomicsEffect of SRI-41315 on translation termination in rabbit reticulocyte lysate-based in vitro translation system
Effect of SRI-41315 on translation termination in rabbit reticulocyte lysate-based in vitro translation system
PRJNA1046496 | ENA
GenomicsRibosome profiling under ABCE1 depletion to study aberrant translation termination
Ribosome profiling under ABCE1 depletion to study aberrant translation termination
PRJNA599943 | ENA
TranscriptomicsWide-spread disruption of transcription termination in HSV-1 infection: Next-generation sequencing of translational activityd by ribosome profiling
Primary human foreskin fibroblasts (HFF) were infected with wild-type simplex virus 1 (HSV-1) strain 17 at a multiplicity of infection (MOI) of 10. Ribosome profiling was performed at various times during infection with minor modification to the protocol described in Stern-Ginossar N et al., Science...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-60040 | biostudies-arrayexpress
ProteomicsGenome-wide effects of the antimicrobial peptide apidaecin on translation termination
Proline-rich antimicrobial peptide apidaecin (Api) inhibits bacterial protein synthesis in a distinctive way. In vitro biochemical and structural studies showed that Api binds in the nascent peptide exit tunnel of the ribosome that has completed translation of the gene and has released the newly-syn...
ORGANISM(S): Escherichia coli 
2020-10-05 | PXD019012 | Pride
Apidaecin Translation termination Lc-ms Peptide E. coli 
GenomicsCircadian clock control of ribosome composition promotes rhythmic translation and termination fidelity [RNA-Seq]
Circadian clock control of ribosome composition promotes rhythmic translation and termination fidelity [RNA-Seq]
PRJNA1188121 | ENA
GenomicsCircadian clock control of ribosome composition promotes rhythmic translation and termination fidelity [Ribo-Seq]
Circadian clock control of ribosome composition promotes rhythmic translation and termination fidelity [Ribo-Seq]
PRJNA1188122 | ENA
TranscriptomicsCorrecting Direct Effects of Ethanol on Translation and Transcription Machinery Confers Ethanol Tolerance in Bacteria [Ribosome_Profiling]
The molecular mechanisms of ethanol toxicity and tolerance in bacteria, while important for biotechnology and bioenergy applications, remain incompletely understood. Genetic studies have identified potential cellular targets for ethanol and revealed multiple mechanisms of tolerance, but it remains d...
ORGANISM(S): Escherichia coli 
2014-06-18 | E-GEOD-56372 | biostudies-arrayexpress
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