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ProteomicsEvaluation of iTRAQ and SWATH-MS for the quantification of proteins associated with insulin resistance in human duodenal biopsy samples
Insulin resistance (IR) is associated with increased production of triglyceride-rich lipoproteins of intestinal origin. In order to assess whether insulin resistance affects the proteins involved in lipid metabolism, we used two mass spectrometry based quantitative proteomics techniques to compare t...
ORGANISM(S): Homo sapiens (Human) 
2015-08-26 | PXD001506 | Pride
Human duodenum Swath-ms Quantitative proteomics Itraq 
TranscriptomicsComparative genomic hybridization of strains of Leishmania infantum, Leishmania major and Leishmania tarentolae
The genomic DNAs of strains JPCM5 and 263 of L. infantum, strains LV39 and Friedlin of L. major and strains Parrot-TarII and S125 of L. tarentolae were used in comparative genomic hybridizations to reveal the intra-species and inter-species gene content, and to validate L. tarentolae Parrot-TarII ge...
ORGANISM(S): Leishmania tarentolae 
2011-10-20 | E-GEOD-27184 | biostudies-arrayexpress
TranscriptomicsLeishmania donovani amastigotes: Nelfinavir (NFV)-sensitive (control) vs Nelfinavir-resistant [Comparative Genomic Hybridization (DNA) profiling]
Drug resistance is a major public health challenge in Leishmaniasis chemotherapy, particularly in the case of emerging Leishmania/HIV-1 co-infections. Recently, we have delineated the mechanism of cell death induced by the HIV-1 protease inhibitor, Nelfinavir, in the Leishmania parasite. In order to...
ORGANISM(S): Leishmania donovani 
2013-06-27 | E-GEOD-42195 | biostudies-arrayexpress
TranscriptomicsLeishmania donovani amastigotes: Nelfinavir (NFV)-sensitive (control) vs Nelfinavir-resistant
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Leishmania donovani 
2013-06-27 | E-GEOD-42197 | biostudies-arrayexpress
TranscriptomicsLeishmania donovani amastigotes: Nelfinavir (NFV)-sensitive (control) vs Nelfinavir-resistant [RNA expression profiling]
Drug resistance is a major public health challenge in Leishmaniasis chemotherapy, particularly in the case of emerging Leishmania/HIV-1 co-infections. Recently, we have delineated the mechanism of cell death induced by the HIV-1 protease inhibitor, Nelfinavir, in the Leishmania parasite. In order to...
ORGANISM(S): Leishmania donovani 
2013-06-27 | E-GEOD-42196 | biostudies-arrayexpress
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