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ProteomicstRF-22 RNA pulldown and Co-IP followed by LC-MS/MS in human cell samples
tRNA-derived fragments (tRFs) play a crucial role in tumor progression. However, whether and how tRFs regulate the immune response in esophageal squamous cell carcinoma (ESCC) and their potential clinical applications remain unclear. tRF-22 enhances myeloid-derived suppressor cells (MDSCs) infiltrat...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD057698 | Pride
Human Cell Trf-22 Escc Lc-ms/ms 
UnknowntRNA-Derived Fragment tRF-22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma.
Not available
S-EPMC12767015 | biostudies-literature
UnknownTargeting choroidal vasculopathy via up-regulation of tRNA-derived fragment tRF-22 expression for controlling progression of myopia.
Not available
S-EPMC10290315 | biostudies-literature
Genomics
The tRF-22-8BWS7K092 released by macrophage-derived exosomes regulates lipopolysaccharide induced acute lung injury by targeting IGF2BP3/ZFP36 to induce ferroptosis
PRJNA1012848 | ENA
Genomics
Alveolar macrophage exosomal tRNA-derived fragments tRF-22-8BWS7K092 promote ferroptosis to involve in acute lung injury
PRJNA756415 | ENA
TranscriptomicsDiurnal transcriptome landscape of a multi-tissue response to time restricted feeding in mammals
Time-restricted feeding (TRF) is an emerging behavioral nutrition intervention that sustains a daily cycle of feeding and fasting. TRF in animals and humans has shown pleiotropic health benefits arising from multiple organ systems, yet the molecular basis of TRF is not well understood. We subjected ...
ORGANISM(S): Mus musculus 
2022-12-20 | GSE190389 | GEO
TranscriptomicsLTR-retrotransposon control by tRNA-derived small RNA
Transposon reactivation is an inherent danger in cells that lose epigenetic silencing during developmental reprogramming. In the mouse, LTR-retrotransposons, or endogenous retroviruses (ERV), account for most novel insertions and are expressed in the absence of histone H3 Lysine 9 trimethylation in ...
ORGANISM(S): Homo sapiens Mus musculus 
2017-06-29 | GSE82199 | GEO
UnknownDiurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals.
Not available
S-EPMC10026518 | biostudies-literature
GenomicsSmall RNAseq using tumor-derived extracellular vesicles
RNA modifications play important roles in cellular processes, and their dysregulation has been linked to various diseases, including cancer. As extracellular vesicles (EVs) contain various RNAs, it is assumed that these can be modified. However, the presence of such modified transcripts has not been...
ORGANISM(S): Homo sapiens 
2024-05-20 | GSE267953 | GEO
UnknownComprehensive Analysis of a tRNA-Derived Small RNA in Colorectal Cancer.
Not available
S-EPMC8371552 | biostudies-literature
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