Escc - OmicsDI

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Department of Radiation Oncology, Qilu Hospital of Shandong University, Jinan, China. (1)
Department of Thoracic Surgery and Lung Transplantation, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China (1)
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Institute of Bioinformatics, International Tech Park, Bangalore 560066, India (1)
MOE Key Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China. (1)
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Aberrant accumulation of cyclin D1 rewires glutamine metabolism via loss of IDH3 generating metabolic vulnerability in ESCC and HNSCC

Excessive cyclin D1 accumulation is a frequent oncogenic event in head and neck squamous cell carcinoma (HNSCC) and esophageal squamous cell carcinoma (ESCC). Although classically associated with enhanced proliferation and genomic instability, we reveal that cyclin D1 dysregulation induces unexpe...

2026-08-24 | MTBLS13687 | MetaboLights

Expression data comparing KYSE-140 ESCC cell line CD90+ and CD90- cells

To identify candidate genes involved in enhanced tumorigenicity and metastasis of CD90+ esophageal tumor-initiating cells. The esophageal squamous carcinoma cell (ESCC) cell line KYSE-140 was sorted into CD90+ and CD90- populations by flow cytometry. Total RNA was analyzed on Affymetrix Human Genome...

ORGANISM(S): Homo sapiens

2013-03-23 | E-GEOD-37949 | biostudies-arrayexpress

Analysis of genomic instability in esophageal squamous cell carcinoma (ESCC)

To characterize genomic instability in esophageal squamous cell carcinoma, we examined loss of heterozygosity, copy number loss, and copy number gain in ESCC patients from a high-risk region of China. Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted fr...

ORGANISM(S): Homo sapiens

2010-04-10 | E-GEOD-15526 | biostudies-arrayexpress

Identification of a Novel Angiogenesis and Tumor Suppressor Gene Rab25 in Esophageal Squamous Cell Carcinoma

Twelve clinical samples from human esophageal squamous cell carcinoma (ESCC) (seven tumors and five non-tumors) were sequenced using Illumina high-throughput sequencing and the RNA-Seq profiling was investigated with 1730 genes significantly differentially expressed. The gene Rab25 was found to be d...

ORGANISM(S): Homo sapiens

2012-12-05 | E-GEOD-32424 | biostudies-arrayexpress

Analysis of gene expression in esophageal squamous cell carcinoma (ESCC)

To characterize gene expression in esophageal squamous cell carcinoma, we examined gene expression in tumor and matched normal adjacent tissue from 17 ESCC patients from a high-risk region of China. RNA was extracted from 17 micro-dissected tumor and matched normal tissue pairs using the PureLink Mi...

ORGANISM(S): Homo sapiens

2011-03-15 | E-GEOD-20347 | biostudies-arrayexpress

Proteome of ESCC identified by LC-MS/MS

Protein identification in esophageal squamous cell carcinoma(ESCC) was performed,we explored the proteomic landscape in ESCC and attempted to perform clinical-related patient classification based on ESCC proteome.

ORGANISM(S): Homo sapiens (Human)

2026-06-15 | PXD053809 | Pride

Lc-ms Escc

Differential protein expression between ESCC and normal tissues

To understand the difference of protein expression between paired esophageal squamous cell carcinoma (ESCC) and adjacent normal tissues, we collected 10 paired ESCC and normal tissues from surgical resected specimems for high-throughput proteomic experiments. From comparative analysis, the dysregula...

ORGANISM(S): Homo sapiens (Human)

2020-08-11 | PXD019834 | Pride

Protein expression Escc

The dataset to discover ESCC related proteins

To discover ESCC related proteins, we used SWATH to quantify the protein abundance between ESCC and adjacent tissues. Briefly, we pooled 10 ESCCtissues and their corresponding adjacent tissues for SWATH acquisition with three replicates.Three DDA repeats were also acquired with the pooled 10-paired ...

ORGANISM(S): Homo sapiens (Human)

2015-09-22 | PXD001764 | Pride

Dda Tissue Swath Escc

Affymetrix SNP array data for esophageal squamous cell carcinoma (ESCC) samples

We demonstrate that blood and esophageal tissues shared similar DNA methylation patterns within the same individual,suggesting an influence of genetic background on DNA methylation. Recent studies have shown a genetic influence on gene expression variation, chromatin, and DNA methylation. However,...

ORGANISM(S): Homo sapiens

2010-08-02 | E-GEOD-20123 | biostudies-arrayexpress

Epigenomics analysis of ESCC

PRJNA499092 | ENA

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